HEXAMETHONIUM MONOTARTRATE Meaning and
Definition
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Hexamethonium monotartrate is a chemical compound belonging to the class of ganglionic blocking agents or ganglionic blockers. It is a derivative of prominent antihypertensive medications used to lower high blood pressure by impeding the transmission of nerve impulses in the ganglia of the autonomic nervous system. Hexamethonium monotartrate specifically prevents the nicotinic cholinergic receptors located in the ganglia, which connect the sympathetic and parasympathetic nerves, from being activated. This property makes it an effective antihypertensive agent by blocking the transmission of nerve signals that cause blood vessels to constrict.
When administered orally or intravenously, hexamethonium monotartrate is readily absorbed by the body and distributed throughout the peripheral tissues. Due to its positively charged structure, it cannot effectively pass through cell membranes, limiting its action primarily to the extracellular space. It has a long duration of action and tends to accumulate in body tissues after multiple doses, allowing for sustained blood pressure control.
Common side effects of hexamethonium monotartrate include dry mouth, constipation, blurred vision, and dizziness due to its central nervous system effects. Additionally, it may cause urinary retention, decreased sweating, and reduced gastrointestinal motility. Rare but severe adverse effects may include orthostatic hypotension, paralysis of the intestine (paralytic ileus), and sensitivity reactions ranging from rashes to anaphylaxis.
Overall, hexamethonium monotartrate is a pharmacological compound with well-established antihypertensive properties by blocking ganglionic transmission, which ultimately results in reduced blood pressure. Its therapeutic use requires careful monitoring and supervision by healthcare professionals.
Common Misspellings for HEXAMETHONIUM MONOTARTRATE
- gexamethonium monotartrate
- bexamethonium monotartrate
- nexamethonium monotartrate
- jexamethonium monotartrate
- uexamethonium monotartrate
- yexamethonium monotartrate
- hwxamethonium monotartrate
- hsxamethonium monotartrate
- hdxamethonium monotartrate
- hrxamethonium monotartrate
- h4xamethonium monotartrate
- h3xamethonium monotartrate
- hezamethonium monotartrate
- hecamethonium monotartrate
- hedamethonium monotartrate
- hesamethonium monotartrate
- hexzmethonium monotartrate
- hexsmethonium monotartrate
- hexwmethonium monotartrate
- hexqmethonium monotartrate
Etymology of HEXAMETHONIUM MONOTARTRATE
The etymology of the word "Hexamethonium Monotartrate" can be broken down as follows:
1. Hexamethonium: The prefix "hexa-" comes from the Greek word "hex" meaning six. "Metho-" comes from the Greek word "methy" meaning wine. "Onium" is a suffix used in chemistry to denote a positively charged ion. Therefore, "hexamethonium" refers to a cation with six methyl groups attached.
2. Monotartrate: "Mono-" is a prefix meaning one in Greek. "Tartrate" refers to the salt or ester of tartaric acid. Therefore, "monotartrate" signifies a compound consisting of one molecule of tartaric acid combined with another molecule.
