GUANIDINE HYDROCHLORIDE Meaning and
Definition
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Guanidine hydrochloride is a chemical compound with the molecular formula CH5N3·HCl. It is a white crystalline powder that is highly soluble in water and has a strong and distinct odor. Guanidine hydrochloride is derived from guanine, a nitrogenous base found in DNA and RNA.
In terms of its chemical properties, guanidine hydrochloride is an organic salt that belongs to the class of guanidinium compounds. It possesses a strong basicity due to the presence of three amino groups, allowing it to act as a cationic nucleophile in various chemical reactions.
Guanidine hydrochloride is widely used in the field of biochemistry and molecular biology. It is most commonly used as a denaturant in protein purification and analysis. Due to its ability to disrupt the non-covalent bonds and protein folding, it helps in unfolding the native proteins for further biochemical studies or isolation of specific protein components.
Furthermore, guanidine hydrochloride is used as a chaotropic agent in nucleic acid isolation and purification procedures. It helps to disrupt the hydrogen bonding between nucleic acids and proteins, facilitating the release of nucleic acids from cellular components, thereby aiding their extraction and subsequent analysis.
Apart from its biological applications, guanidine hydrochloride is also used as a reagent in organic synthesis, particularly in the synthesis of various guanidine derivatives. It is known to participate in reactions like carbonyl condensation, nucleophilic substitution, and cyclization reactions.
It is important to handle guanidine hydrochloride with caution as it is highly toxic and can cause severe skin and eye irritation. Proper safety measures should be followed while working with this compound to ensure the protection of individuals and the environment.
Common Misspellings for GUANIDINE HYDROCHLORIDE
- fuanidine hydrochloride
- vuanidine hydrochloride
- buanidine hydrochloride
- huanidine hydrochloride
- yuanidine hydrochloride
- tuanidine hydrochloride
- gyanidine hydrochloride
- ghanidine hydrochloride
- gjanidine hydrochloride
- gianidine hydrochloride
- g8anidine hydrochloride
- g7anidine hydrochloride
- guznidine hydrochloride
- gusnidine hydrochloride
- guwnidine hydrochloride
- guqnidine hydrochloride
- guabidine hydrochloride
- guamidine hydrochloride
- guajidine hydrochloride
- guahidine hydrochloride
Etymology of GUANIDINE HYDROCHLORIDE
The word "Guanidine" is derived from "guanine", a nitrogenous base found in DNA and RNA. It was first isolated from guano, hence the name.
"Hydrochloride" refers to the salt form of guanidine that is formed by reacting guanidine with hydrochloric acid (HCl). The term "hydrochloride" indicates that the compound contains the chloride ion.
