How Do You Spell GAMMA GLUTAMYLCYCLOTRANSFERASE?

Pronunciation: [ɡˈamə ɡlˈuːtɐmˌɪlsa͡ɪklˌɒtɹɐnsfˌɜːɹe͡ɪz] (IPA)

The word "gamma Glutamylcyclotransferase" is a mouthful to pronounce and spell, but its phonetic transcription in IPA makes it easier to understand. The first sound is /ɡ/, followed by /æ/ as in "cat." Then comes /m/ and /ə/ as in "sofa." The next sounds are /ɡlʌtəmɪl/ and /saɪkloʊtrænsfɜrˌeɪz/. The final sound is /-eɪs/ as in "race." This enzyme is often shortened to GGT, which simplifies its pronunciation and spelling. Understanding the phonetic transcription can help in correctly pronouncing and spelling challenging scientific terms.

GAMMA GLUTAMYLCYCLOTRANSFERASE Meaning and Definition

1. Gamma glutamylcyclotransferase (GGCT), also known as gamma-glutamyltranspeptidase (GGT), is an enzyme found in various tissues throughout the body, primarily in the liver and kidneys. It plays a crucial role in the metabolism and processing of glutathione, a powerful antioxidant that helps protect cells from damage.

   GGCT is responsible for transferring the gamma-glutamyl group from glutathione to other amino acids, peptides, or molecules, leading to the breakdown of glutathione and the formation of gamma-glutamyl compounds. This transfer process is essential for the transport and recycling of glutathione, which aids in detoxification reactions, the maintenance of intracellular redox balance, and the regulation of cellular signaling pathways.

   Measuring the levels of GGCT in blood can be used as a diagnostic marker for liver and bile duct disorders, as the enzyme is usually highly concentrated in these organs. Elevated GGCT levels are often associated with liver injury, hepatobiliary diseases, and other conditions such as alcohol abuse, hepatitis, cirrhosis, and bile duct obstruction.

   In addition to its clinical significance, GGCT has been extensively studied for its potential role in cancer development and treatment. It has been found to be involved in tumor progression, drug resistance, and metastasis in various types of cancers, making it a target for therapeutic intervention and a potential biomarker for cancer diagnosis and prognosis.

   In summary, gamma-glutamylcyclotransferase is an enzyme that plays a crucial role in glutathione metabolism, detoxification, and maintenance of cellular redox balance. It is clinically relevant in liver and bile duct disorders and has emerged as a potential target in cancer research.

Common Misspellings for GAMMA GLUTAMYLCYCLOTRANSFERASE

• famma glutamylcyclotransferase
• vamma glutamylcyclotransferase
• bamma glutamylcyclotransferase
• hamma glutamylcyclotransferase
• yamma glutamylcyclotransferase
• tamma glutamylcyclotransferase
• gzmma glutamylcyclotransferase
• gsmma glutamylcyclotransferase
• gwmma glutamylcyclotransferase
• gqmma glutamylcyclotransferase
• ganma glutamylcyclotransferase
• gakma glutamylcyclotransferase
• gajma glutamylcyclotransferase
• gamna glutamylcyclotransferase
• gamka glutamylcyclotransferase
• gamja glutamylcyclotransferase
• gammz glutamylcyclotransferase
• gamms glutamylcyclotransferase
• gammw glutamylcyclotransferase
• gammq glutamylcyclotransferase

Etymology of GAMMA GLUTAMYLCYCLOTRANSFERASE

The word "gamma Glutamylcyclotransferase" comes from a combination of several components:

1. Gamma: The term "gamma" comes from the third letter of the Greek alphabet, gamma (Γ). In scientific terminology, "gamma" is often used to refer to the third in a series or the third position of a compound.

2. Glutamyl: The term "glutamyl" is derived from the amino acid glutamic acid, which is one of the 20 standard amino acids found in proteins. It is derived from the Latin word "gluten", meaning glue, referencing its presence in protein structures.

3.