How Do You Spell GAMMA GLUTAMYL TRANSPEPTIDASE?

Pronunciation: [ɡˈamə ɡlˈuːtɐmˌɪl tɹanspˈɛptɪdˌe͡ɪs] (IPA)

Gamma Glutamyl Transpeptidase is a mouthful of a word, and its spelling reflects its complex pronunciation. Using the International Phonetic Alphabet (IPA), the correct pronunciation is ɡæmə ˌɡluːtəmɪl trænzˈpɛptɪdeɪs. The first syllable, "gamma," is pronounced with a hard "g" sound, followed by the stress on the second syllable. The "a" in "gamma" is t̬ʰen pronounced like the "a" in "cat" while the "u" in "glutamyl" sounds like "oo." The final syllable, "peptidase," is emphasized, with the "a" pronounced like "ay" as in "day."

GAMMA GLUTAMYL TRANSPEPTIDASE Meaning and Definition

1. Gamma-glutamyl transpeptidase (GGT) is an enzyme that plays a crucial role in the metabolism of glutathione. It is primarily found in the liver, but also exists in other organs such as the kidneys, pancreas, and small intestine. GGT is involved in the transfer of amino acids across cell membranes and in the degradation of extracellular glutathione.

   The function of gamma-glutamyl transpeptidase is to catalyze the transfer of gamma-glutamyl groups from molecules such as glutathione to an acceptor compound. This enzymatic reaction results in the cleavage of the gamma-glutamyl bond and the formation of a new peptide bond with the acceptor molecule. The transferred gamma-glutamyl groups can then be further metabolized or transported across cell membranes.

   GGT is widely used as a diagnostic marker for liver diseases, as its levels in blood serum increase in response to liver damage or dysfunction. Elevated GGT levels may indicate liver conditions such as hepatitis, cirrhosis, or alcohol abuse. Additionally, it has also been associated with diseases outside of the liver, including cardiovascular diseases, diabetes, and certain types of cancer.

   In summary, gamma-glutamyl transpeptidase is an enzyme that facilitates the transfer of gamma-glutamyl groups between molecules. Its main role is in the metabolism of glutathione, and it is primarily found in the liver. GGT levels in the blood can provide important diagnostic information about liver health and other diseases.

Common Misspellings for GAMMA GLUTAMYL TRANSPEPTIDASE

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