How Do You Spell FUMARASE DEHYDROGENASE?

Pronunciation: [fjˈuːmɐɹˌe͡ɪz dˌiːha͡ɪdɹˈə͡ʊd͡ʒne͡ɪs] (IPA)

The word "fumarase dehydrogenase" is spelled as /ˈfjuːməreɪz diːhaɪdrədʒəneɪs/ in IPA phonetic transcription. This lengthy word refers to an enzyme involved in the citric acid cycle, responsible for converting fumarate to malate. The word is a combination of "fumarase" and "dehydrogenase", with the letter "u" pronounced as "oo", "a" as "ay", "e" as "ee", and "i" as "eye" in IPA. The correct spelling of technical terms like this is crucial in scientific research to avoid miscommunications and misunderstandings among researchers.

FUMARASE DEHYDROGENASE Meaning and Definition

1. Fumarase dehydrogenase, also known as succinate dehydrogenase or succinate-coenzyme Q reductase, is an enzyme that plays a crucial role in the tricarboxylic acid (TCA) cycle, also known as the Krebs cycle or citric acid cycle. It is responsible for the conversion of succinate into fumarate, a key step in the cycle.

   Fumarase dehydrogenase is a flavoprotein enzyme, meaning it possesses a flavin prosthetic group, usually FAD (flavin adenine dinucleotide), which serves as an electron carrier during the conversion process. This enzyme also incorporates iron-sulfur clusters as essential cofactors. Fumarase dehydrogenase is found in the inner mitochondrial membrane of eukaryotic cells and the cytoplasm of prokaryotic cells.

   The reaction catalyzed by fumarase dehydrogenase is an oxidation reduction reaction, where succinate is oxidized to fumarate. Simultaneously, the enzyme transfers two electrons from succinate to FAD, which is reduced to FADH2. FADH2 then donates its electrons to the electron transport chain, contributing to the production of adenosine triphosphate (ATP) through oxidative phosphorylation.

   Furthermore, fumarase dehydrogenase is a critical regulator of cellular metabolism, as it is involved in linking the TCA cycle with other metabolic pathways, such as the electron transport chain and fatty acid metabolism. Dysfunction or deficiency of this enzyme has been linked to various human diseases, including hereditary paraganglioma and syndromes associated with mitochondrial complex II deficiencies.

   In summary, fumarase dehydrogenase is an enzyme that plays a vital

Common Misspellings for FUMARASE DEHYDROGENASE

• dumarase dehydrogenase
• cumarase dehydrogenase
• vumarase dehydrogenase
• gumarase dehydrogenase
• tumarase dehydrogenase
• rumarase dehydrogenase
• fymarase dehydrogenase
• fhmarase dehydrogenase
• fjmarase dehydrogenase
• fimarase dehydrogenase
• f8marase dehydrogenase
• f7marase dehydrogenase
• funarase dehydrogenase
• fukarase dehydrogenase
• fujarase dehydrogenase
• fumzrase dehydrogenase
• fumsrase dehydrogenase
• fumwrase dehydrogenase
• fumqrase dehydrogenase
• fumaease dehydrogenase

Etymology of FUMARASE DEHYDROGENASE

The word "fumarase" has its etymology from the Latin "fumus" meaning "smoke" and the suffix "-ase" indicating an enzyme. Fumarase is an enzyme that catalyzes the reversible hydration/dehydration of fumarate, an intermediate compound in the citric acid cycle.

The word "dehydrogenase" comes from the Greek roots "de-", meaning "removal" or "without", "hydro-", meaning "water", and "-gen", meaning "to produce". Dehydrogenase is an enzyme that catalyzes the removal of hydrogen atoms from a molecule.

So, "fumarase dehydrogenase" is a combination of these two terms to describe an enzyme that likely involves the removal of hydrogen atoms from a molecule related to fumarate.

Plural form of FUMARASE DEHYDROGENASE is FUMARASE DEHYDROGENASES