DEFA PROTEIN Meaning and
Definition
-
DEFA protein refers to a group of antimicrobial peptides, specifically defensins, that are produced by the human body. Defensins are small, cationic peptides that are a crucial part of the innate immune system and help defend the body against invading pathogens such as bacteria, viruses, and fungi.
DEFA protein is primarily synthesized and released by specialized cells of the immune system called neutrophils and Paneth cells, which are found in the small intestine. Neutrophils are white blood cells that play a significant role in the body's defense against infections, while Paneth cells are a type of cell located in the small intestine's lining, providing an important line of defense against intestinal bacteria.
The DEFA protein is characterized by its ability to disrupt the cell membrane of microbial pathogens, leading to their destruction. Furthermore, it possesses immunomodulatory properties, helping regulate the immune response during infection or inflammation.
Deficiencies or abnormalities in DEFA protein expression or function have been associated with various diseases and conditions, including inflammatory bowel disease (IBD), autoimmune disorders, and certain types of cancer. Conversely, elevated DEFA protein levels have been observed in some infectious diseases, suggesting its increased production as part of the body's defense mechanism.
Overall, DEFA protein represents a crucial component of the innate immune system, aiding in the body's defense against microbial pathogens and helping maintain an appropriate immune response during disease or infection.
Common Misspellings for DEFA PROTEIN
- sefa protein
- xefa protein
- cefa protein
- fefa protein
- refa protein
- eefa protein
- dwfa protein
- dsfa protein
- ddfa protein
- drfa protein
- d4fa protein
- d3fa protein
- deda protein
- deca protein
- deva protein
- dega protein
- deta protein
- dera protein
- defz protein
- defs protein
Etymology of DEFA PROTEIN
The word "DEFA protein" stands for "human defensin alpha protein". The etymology of the term "defensin" originates from the Latin word "defendere" which means "to ward off" or "to defend". Defensins are a group of antimicrobial peptides that play a crucial role in the innate immune system by helping to protect the body against various pathogens, including bacteria, fungi, and viruses. The "alpha" in DEFA protein represents a specific subclass of human defensins.
