D TUBOCURARE Meaning and
Definition
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D Tubocurare, also known as d-tubocurarine, is a naturally occurring toxic alkaloid derived from plants of the Chondrodendron genus, particularly Chondrodendron tomentosum and Chondrodendron amazonicum. It is classified as a non-depolarizing neuromuscular blocking agent that acts as a competitive antagonist of the neurotransmitter acetylcholine at the motor endplate of skeletal muscles.
D Tubocurare has been traditionally used by indigenous tribes in South America for many centuries as a poison for hunting purposes. In the field of medicine, it has been employed as a muscle relaxant during surgical procedures, especially in anesthesia, due to its prominent capacity to induce skeletal muscle paralysis.
Being a non-depolarizing neuromuscular blocking agent, d Tubocurare blocks the action of acetylcholine by binding to the nicotinic receptors on the motor endplate of skeletal muscles, subsequently preventing nerve impulse transmission and resulting in relaxation or paralysis of the affected muscles. This pharmacological action allows surgical intervention without muscle contractions interfering with the procedure.
However, d Tubocurare is associated with some adverse effects, including respiratory depression, histamine release, and cardiovascular effects, such as hypotension and tachycardia. Additionally, this alkaloid has a slow onset and a relatively long duration of action, requiring careful monitoring during its administration.
In modern medicine, the use of d Tubocurare has decreased significantly due to the introduction of newer, more short-acting neuromuscular blocking agents with a more desirable profile of side effects and easier dosing.
Common Misspellings for D TUBOCURARE
- d Tubocura2e
- d Tubocurabe
- d Tubocuraze
- d Tubocurave
- d Tubocurape
- d Tubocurase
- d Tubocuraru
- d Tubocurarm
- d Tubocurara
- d Tubocurarg
- d t ubocurare
- d tu bocurare
- d tub ocurare
- d tubo curare
- d tuboc urare
- d tubocu rare
- d tubocur are
- d tubocura re
- d tubocurar e
Etymology of D TUBOCURARE
The word "d-tubocurare" is derived from the combination of three components: "d-" which indicates the specific chemical structure of the compound, "tubo" in reference to the South American plant Chondrodendron tomentosum, also known as "tube" or "tube vine", and "curare", a term used for a group of natural plant-derived toxins traditionally used by indigenous South American tribes as a poison for arrows or blowgun darts.
The "d-" prefix in "d-tubocurare" refers to the stereochemistry of the molecule, indicating the position of the different atoms or functional groups in three-dimensional space. In this case, it refers to the specific orientation of the chemical bond in one of the structural isomers of tubocurarine.
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