The correct spelling of the medical condition "combined sclerosis" can be a source of confusion for many people. The word "sclerosis" is spelled with an "s" rather than a "c" in this case, and the word "combined" is spelled with a "b" rather than a "c". The correct pronunciation of "combined sclerosis" is /kəmˈbaɪnd sklɪˈroʊsɪs/, with the stress on the second syllable of "sclerosis". This term refers to a type of multiple sclerosis that affects both the white matter and gray matter of the central nervous system.
Combined sclerosis, also known as mixed sclerosis, refers to a medical condition characterized by the simultaneous presence of both diffuse or disseminated sclerosis and focal sclerosis within the central nervous system (CNS). The CNS comprises the brain and spinal cord. This condition involves the progressive and chronic inflammation and demyelination of nerve fibers in various regions of the CNS.
The term "combined sclerosis" is used to describe the coexistence of different types of sclerosis in the same patient, typically referring to the simultaneous presence of both multiple sclerosis (MS) and arteriosclerosis. Multiple sclerosis is an autoimmune disease where the body's immune system mistakenly attacks the protective covering of nerve fibers called myelin, leading to communication problems between the brain and the rest of the body. Arteriosclerosis, on the other hand, refers to the hardening and narrowing of arteries due to the build-up of fatty deposits and plaque.
The symptoms of combined sclerosis can vary depending on the specific types of sclerosis involved and the affected areas of the CNS. Common symptoms may include muscle weakness, impaired coordination and balance, sensory disturbances, cognitive difficulties, and fatigue. Treatment options for combined sclerosis may involve a combination of medications to manage symptoms and slow disease progression, as well as lifestyle modifications and various therapies aimed at improving quality of life.
A form of sclerosis of the spinal cord involving both posterior and lateral columns.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word sclerosis comes from the Greek word askleros, meaning hardness. It refers to the abnormal hardening or thickening of body tissues.
Combined sclerosis is a term used to describe a condition known as multiple sclerosis (MS), which is a chronic autoimmune disease that affects the central nervous system. The term combined in this context emphasizes that multiple areas of the central nervous system may be affected by the sclerosis. In MS, the protective covering of nerve fibers (myelin) is damaged, leading to communication problems between the brain and the rest of the body. The term combined sclerosis has since been replaced by the more commonly used term multiple sclerosis.