CHEMOKINE RECEPTOR Meaning and
Definition
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A chemokine receptor is a type of cell surface receptor that specifically binds to chemokines, a family of small signaling proteins involved in immune responses and inflammation. Chemokine receptors play a pivotal role in the migration and activation of various immune cells, including leukocytes, within the body.
Chemokine receptors are typically found on the surface of immune cells, such as T-cells, B-cells, macrophages, and dendritic cells, as well as on endothelial cells that line blood vessels. They are responsible for sensing and responding to the presence of chemokines, which act as chemoattractants by guiding the movement of immune cells towards sites of infection, injury, or inflammation.
Upon binding to their corresponding chemokine ligands, chemokine receptors trigger intracellular signaling cascades, leading to various cellular responses. This includes changes in cell adhesion, cytoskeletal rearrangement, and secretion of other immune cell mediators. These actions ultimately regulate the recruitment, activation, and localization of immune cells within tissues, allowing for an effective immune response and tissue homeostasis.
Abnormalities in chemokine receptors or their ligands can have significant implications for human health. Dysregulation of chemokine signaling has been associated with various diseases, including inflammatory disorders, autoimmune diseases, and cancer. Therefore, chemokine receptors and their ligands represent attractive targets for the development of novel therapeutics aimed at modulating immune responses and treating such conditions.
Common Misspellings for CHEMOKINE RECEPTOR
- xhemokine receptor
- vhemokine receptor
- fhemokine receptor
- dhemokine receptor
- cgemokine receptor
- cbemokine receptor
- cnemokine receptor
- cjemokine receptor
- cuemokine receptor
- cyemokine receptor
- chwmokine receptor
- chsmokine receptor
- chdmokine receptor
- chrmokine receptor
- ch4mokine receptor
- ch3mokine receptor
- chenokine receptor
- chekokine receptor
- chejokine receptor
- chemikine receptor
Etymology of CHEMOKINE RECEPTOR
The word "chemokine" is derived from the combination of "chemo-" which refers to chemicals or chemistry, and "-kine" which is short for "cytokine", a type of signaling molecule involved in immune responses. "Receptor" refers to a molecule or structure on the surface of a cell that recognizes and binds to specific molecules, such as chemokines.
Therefore, the term "chemokine receptor" is used to describe a type of cell surface receptor that interacts with chemokines, allowing the cell to respond to chemotactic signals and participate in immune responses. The etymology of "chemokine receptor" can be understood by breaking down the individual components of the term.
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