Celiprolol is a pharmaceutical drug that belongs to the selective beta-1-adrenoceptor antagonist class, commonly known as beta-blockers. It is primarily used in the treatment of hypertension, or high blood pressure. By blocking the effects of certain stress hormones, such as adrenaline, celiprolol helps to relax and widen the blood vessels. This action further decreases the workload on the heart and allows the blood to flow more easily, thus reducing the overall blood pressure.
Additionally, celiprolol exhibits intrinsic sympathomimetic activity, meaning that it can also stimulate the beta receptors in a weakened or partial manner. This property differentiates celiprolol from other beta-blockers, as it has the potential to cause less bradycardia (slow heart rate) and decreased cardiac output.
Celiprolol is also used for the management of angina pectoris, a condition characterized by chest pain or discomfort due to poor blood flow to the heart muscles. By decreasing the demands on the heart and dilating the coronary arteries, celiprolol helps to alleviate the symptoms associated with this condition.
Moreover, celiprolol may have application in the prevention and treatment of migraine headaches, though the exact mechanisms and effectiveness are still being studied.
As with any medication, celiprolol may have side effects, such as fatigue, dizziness, gastrointestinal disturbances, and sexual dysfunction. It is important to follow the prescribed dosage and consult a healthcare professional for proper guidance and monitoring when using celiprolol.
