AZTREONAM Meaning and
Definition
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Aztreonam is a synthetic antibiotic that belongs to the monobactam class of antibiotics. It is primarily used in the treatment of various bacterial infections and is effective against gram-negative bacteria such as Pseudomonas aeruginosa.
Aztreonam works by inhibiting the synthesis of bacterial cell walls, disrupting their structural integrity and leading to cell death. It specifically targets the penicillin-binding proteins (PBPs) that are essential for the formation of the bacterial cell wall. By interfering with the transpeptidation reaction, aztreonam prevents the cross-linking of peptidoglycan chains, crucial for the integrity of the bacterial cell wall.
Its mechanism of action is unique, as it does not affect the normal microbial flora of the body. This feature makes aztreonam particularly valuable in the treatment of infections in patients allergic to penicillins or cephalosporins.
Aztreonam is administered intravenously or by inhalation in the form of a solution. It is rapidly distributed into tissues and exhibits a prolonged elimination half-life, enabling once or twice daily dosing regimens.
Common side effects of aztreonam can include nausea, diarrhea, headache, or rash. Most of these side effects are generally mild, although severe allergic reactions are possible, requiring immediate medical attention.
As with any antibiotic, the appropriate use of aztreonam is critical to prevent the development of antibiotic resistance. Therefore, it is essential to follow the prescribed dosage and complete the full course of treatment unless otherwise directed by a healthcare professional.
Common Misspellings for AZTREONAM
- zztreonam
- sztreonam
- wztreonam
- qztreonam
- axtreonam
- astreonam
- aatreonam
- azrreonam
- azfreonam
- azgreonam
- azyreonam
- az6reonam
- az5reonam
- azteeonam
- aztdeonam
- aztfeonam
- aztteonam
- azt5eonam
- azt4eonam
Etymology of AZTREONAM
The word "aztreonam" is derived from the combination of the prefix "az-" and the word "treonam".
The prefix "az-" in aztreonam is commonly used in chemistry to indicate the presence of an azetidine ring, which is a four-membered nitrogen-containing heterocycle. This prefix denotes the specific chemical structure present in aztreonam.
The term "treonam" is derived from the name of the antibiotic that aztreonam belongs to, called monobactams. Monobactams are a class of beta-lactam antibiotics, characterized by a unique monocyclic beta-lactam structure. The name "treonam" is a combination of "tri-" (meaning three) and "enam" (referring to the double bond in the structure), indicating the three carbon atoms in the ring.
Similar spelling word for AZTREONAM
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