ATHEROGENESIS Meaning and
Definition
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Atherogenesis is a term used in medicine to define the process of atherosclerosis development, which is the progressive narrowing and hardening of arteries. More specifically, atherogenesis refers to the formation and accumulation of atheromas, also known as plaque, within the arterial walls. Atheromas are composed of various substances, including cholesterol, lipids, calcium, and cellular debris.
The process of atherogenesis begins with the infiltration of lipids, particularly low-density lipoproteins (LDL), into the arterial walls, leading to the formation of fatty streaks. These fatty deposits trigger an inflammatory response, attracting immune cells, such as macrophages, which ingest the lipids and transform into foam cells. Over time, the continuous accumulation of foam cells and other substances, such as smooth muscle cells and fibrous tissue, forms a fibrous plaque. This plaque progressively narrows the arterial lumen, impeding blood flow and compromising tissue oxygenation.
Atherogenesis is a complex and multifactorial process influenced by various risk factors, including smoking, high blood pressure, high cholesterol levels, obesity, diabetes, and genetic predisposition. The presence of atheromas can lead to the development of atherosclerotic plaques, and subsequent complications, such as thrombosis, which may result in heart attacks, strokes, or other cardiovascular diseases.
Understanding the mechanisms behind atherogenesis is crucial for developing preventative and therapeutic strategies to reduce the burden of atherosclerosis and its associated complications.
Common Misspellings for ATHEROGENESIS
- ztherogenesis
- stherogenesis
- wtherogenesis
- qtherogenesis
- arherogenesis
- afherogenesis
- agherogenesis
- ayherogenesis
- a6herogenesis
- a5herogenesis
- atgerogenesis
- atberogenesis
- atnerogenesis
- atjerogenesis
- atuerogenesis
- atyerogenesis
- athwrogenesis
- athsrogenesis
- athdrogenesis
Etymology of ATHEROGENESIS
The word "atherogenesis" is derived from the combination of two Greek roots: "athero" and "genesis".
The root "athero" (άθηρο) originates from the Greek word "áthīra" (ἀθήρα), which means "gruel" or "porridge". This term was used to describe the fatty deposits that accumulate within the walls of blood vessels, forming a thickened, gruel-like substance known as atherosclerosis.
The root "genesis" (γένεσις) is derived from the Greek word "génesis" (γένεσις), which translates to "origin" or "creation". It is commonly used in scientific contexts to refer to the process of formation or development.
Similar spelling words for ATHEROGENESIS
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