ANTISENSE OLIGORNA Meaning and
Definition
-
Antisense OligoRNA, also known as antisense oligonucleotide or antisense RNA, is a type of synthetic, single-stranded molecule composed of short sequences of nucleotides. These molecules are designed to bind specifically to complementary target RNA sequences, thus preventing the synthesis of specific proteins that are encoded by those RNA molecules.
The concept of antisense technology involves using these oligonucleotides to interfere with gene expression at the RNA level. By targeting messenger RNA (mRNA) molecules, which carry genetic information from DNA to the ribosomes for protein synthesis, antisense OligoRNAs can prevent the translation of specific proteins. This disruption of protein synthesis makes antisense OligoRNAs potential tools for gene therapy and other therapeutic applications.
Antisense OligoRNA works by binding to its complementary RNA sequence through base pairing, leading to a formation of a RNA-RNA duplex. This binding prevents the mRNA from being "read" by the ribosomes, thereby inhibiting protein production from that particular mRNA. This mechanism highlights the versatile applications of antisense OligoRNA in modulating gene expression levels.
Antisense OligoRNA has gained attention in the field of medicine as a potential treatment for various genetic disorders, viral infections, and cancers. It offers a complementary approach to traditional small molecule drugs and protein-based therapeutics. However, there are challenges to overcome, including delivery into specific target tissues and minimizing off-target effects. Nonetheless, constant advancements and research in this field continue to improve the design and utilization of antisense OligoRNA for therapeutic purposes.
Common Misspellings for ANTISENSE OLIGORNA
- zntisense oligorna
- sntisense oligorna
- wntisense oligorna
- qntisense oligorna
- abtisense oligorna
- amtisense oligorna
- ajtisense oligorna
- ahtisense oligorna
- anrisense oligorna
- anfisense oligorna
- angisense oligorna
- anyisense oligorna
- an6isense oligorna
- an5isense oligorna
- antusense oligorna
- antjsense oligorna
- antksense oligorna
- antosense oligorna
- ant9sense oligorna
- ant8sense oligorna
Etymology of ANTISENSE OLIGORNA
The term "Antisense OligoRNA" can be broken down into its constituent parts:
1. Antisense: The term "antisense" refers to a molecular sequence that is complementary to another sequence of nucleic acids, such as DNA or RNA. It is called "antisense" because it is the reverse or "complement" of the sense sequence.
2. Oligo: The term "oligo" is derived from the Greek word "oligos", meaning "few" or "little". In the context of molecular biology, an "oligo" refers to a short sequence of nucleotides (building blocks of DNA and RNA) typically ranging from about 10 to 50 nucleotides in length.
3. RNA: RNA stands for ribonucleic acid, which is a molecule involved in various biological processes in cells.
Infographic
Add the infographic to your website:
