How Do You Spell ANTISENSE OLIGORIBONUCLEOTIDES?

Pronunciation: [ˌantɪsˈɛns ˈɒlɪɡˌɔːɹɪbˌɒnjuːklˌɪətˌa͡ɪdz] (IPA)

Antisense Oligoribonucleotides, pronounced ˌæntiˈsɛns ˌɒliɡoʊˈraɪboʊˌnjuːkliəˌtaɪdz, are short, single-stranded molecules composed of RNA that can bind to specific messenger RNA (mRNA) molecules. The spelling of this word follows standard English pronunciation rules, with each syllable pronounced as in "ant-i-sense," "ol-i-go," "ri-bo-nu-cle-o-tides." The International Phonetic Alphabet (IPA) can help clarify the word's pronunciation, with symbols representing individual sounds in the English language. Effective communication about medical treatments requires accurate pronunciation, and relying on the IPA can help ensure clarity and precision in medical language.

ANTISENSE OLIGORIBONUCLEOTIDES Meaning and Definition

1. Antisense oligoribonucleotides (ASOs) are short, synthetic nucleic acid molecules typically made of RNA or DNA that are designed to specifically bind to and alter the expression of target RNA molecules. ASOs work by binding to complementary RNA sequences through base-pairing interactions, which can prevent the target RNA from being translated into protein or can induce enzymatic degradation of the RNA.

   ASOs have emerged as powerful tools in molecular biology and therapeutics due to their ability to selectively modulate gene expression. In research settings, ASOs are commonly used to study gene function by selectively inhibiting the expression of specific genes. In therapeutic applications, ASOs are being developed as potential treatments for a wide range of diseases, including genetic disorders, cancer, and viral infections.

   ASOs have several advantages as potential therapeutic agents. First, they can be easily synthesized in the laboratory and modified to enhance their stability and specificity. Additionally, ASOs can be delivered to target cells or tissues by various methods, including injection, encapsulation in nanoparticles, or conjugation to targeting ligands. Furthermore, ASOs can act at different levels of gene expression regulation, including blocking translation, promoting degradation of the target RNA, or modulating alternative splicing.

   Overall, antisense oligoribonucleotides represent a versatile class of molecules with the potential to revolutionize the understanding and treatment of various diseases by selectively modulating gene expression.

Common Misspellings for ANTISENSE OLIGORIBONUCLEOTIDES

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• ant9sense oligoribonucleotides
• ant8sense oligoribonucleotides

Etymology of ANTISENSE OLIGORIBONUCLEOTIDES

The word "Antisense Oligoribonucleotides" has its etymology rooted in the field of molecular biology and genetics. Here's a breakdown of each component:

1. Antisense: The term "antisense" refers to the opposite or complementary strand of a nucleic acid molecule. In molecular biology, the sense strand is the coding strand that serves as a template during transcription, and the antisense strand is the non-coding complementary strand.

2. Oligoribonucleotides: "Oligoribonucleotides" can be broken down into three parts:

- Oligo: Derived from the Greek word "oligos", meaning "few" or "little", oligo- denotes a small number or a few.