AMINO PHOSPHONOVALERIC ACID Meaning and
Definition
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Amino phosphonovaleric acid, commonly known as APV, is an organic compound belonging to the class of phosphonic acids. It is derived from valeric acid and contains an amino group, making it an amino acid derivative. APV has a chemical formula of C5H12NO5P and a molecular weight of approximately 189.1 grams per mole.
APV is primarily used as a pharmaceutical agent and has been studied for its potential therapeutic effects. It acts as an antagonist for the N-methyl-D-aspartate (NMDA) receptor, an important receptor involved in the transmission of nerve signals in the central nervous system. By blocking the action of this receptor, APV has shown to inhibit the release of excitation and promote neuroprotection.
As a pharmaceutical compound, APV has been investigated for its potential use in the treatment of various neurological disorders, including epilepsy and cerebral ischemia. It has demonstrated promising effects in animal studies, showing a reduction in seizure activity and the prevention of neuronal cell death.
In addition to its pharmaceutical applications, APV is also used as a research tool in neuroscience studies. Its ability to selectively block NMDA receptors makes it a valuable tool for investigating the role of these receptors in various physiological and pathological processes.
In summary, amino phosphonovaleric acid (APV) is a phosphonic acid derivative that acts as an antagonist for the NMDA receptor. It has potential therapeutic applications in the treatment of neurological disorders and serves as an important research tool in neuroscience studies.
