AMIDES Meaning and
Definition
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Amides are a class of organic compounds that contain a carbonyl group (C=O) bonded to a nitrogen atom (N). They are derivatives of carboxylic acids in which the hydroxyl group (-OH) has been replaced by an amino group (-NH2) or an organic group derived from ammonia or an amine. The general formula for an amide is RCONH2, where R represents a hydrogen atom or an organic group.
Amides are commonly found in nature and are important building blocks in biological systems. They can be synthesized through various methods, including the reaction between a carboxylic acid and ammonia or an amine, or through the reaction of an acid chloride with ammonia or an amine.
Amides exhibit unique chemical properties due to the presence of the carbonyl and nitrogen groups. They are generally less reactive than their corresponding carboxylic acids and can form hydrogen bonds, which contribute to their high boiling points and melting points. Amides are extensively used in pharmaceuticals, as they can be efficiently absorbed by the body and can interact with various biological targets. They also have applications in the synthesis of polymers, dyes, and solvents, among other industrial products.
In summary, amides are a class of organic compounds that possess a carbonyl group bonded to a nitrogen atom. They play essential roles in biological systems and have wide-ranging applications in industries such as pharmaceuticals and polymers.
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Etymology of AMIDES
The word "amides" has its etymology derived from the Latin term "amidem", which means "amid, in the middle". It is formed by combining the preposition "a-" (meaning "in") with the noun "midem" (meaning "middle"). The Latin term "amidem" later evolved into the Old French word "amide", which ultimately resulted in the word "amides" in Modern English. In chemistry, "amides" refers to a class of organic compounds that are derivatives of carboxylic acids.
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