AMIDE Meaning and
Definition
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Amide is a noun that refers to a class of organic compounds derived from ammonia (NH3) in which one or more hydrogen atoms are replaced by acyl groups (R-C=O), resulting in the general formula R1CONR2R3. The term amide can also specifically refer to the functional group -CONH2, where the carbon atom is bonded to an amino (NH2) group and a carbonyl (C=O) group.
Amides are characterized by the presence of the carbonyl group (C=O) bonded to a nitrogen atom (N), resulting in the amide bond. This bond is planar and has a partial double bond character, imparting both rigidity and stability to amides. The arrangement of atoms in amides allows them to participate in various chemical reactions, making them important building blocks in organic chemistry.
Amides play a crucial role in biological systems, as they are the primary components of proteins and peptides. They serve as the linkages that connect amino acids together, forming long chains that ultimately fold into intricate three-dimensional structures. Additionally, amides are involved in DNA and RNA synthesis, as well as in various metabolic processes.
Overall, amides are important and versatile compounds that have broad applications in pharmaceuticals, polymers, agriculture, and other industries. Their unique chemical and structural properties make them invaluable for drug design and development, as well as for understanding and manipulating biological functions.
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A substance which may be derived from ammonia through the substitution of one or more of the hydrogen atoms by acid or oxidized radicals; the replacement of one hydrogen atom constitutes a primary, that of two hydrogen atoms a secondary, and that of three atoms a tertiary amide.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
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A peculiar chemical substance entering into a large number of compounds.
Etymological and pronouncing dictionary of the English language. By Stormonth, James, Phelp, P. H. Published 1874.
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Etymology of AMIDE
The word "amide" is derived from the Latin word "amidum", which in turn originates from the Greek word "amidein". "Amidein" means "urine" and is a combination of "a", meaning "not", and "mikros", meaning "small". The name "amidein" is attributed to the strong odor of ammonia commonly present in urine. Over time, "amidum" evolved into the English word "amide", which refers to a functional group consisting of a nitrogen atom bonded to a carbonyl carbon and two other groups.
Similar spelling words for AMIDE
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