AGONIST Meaning and
Definition
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An agonist is a term within the field of biology, specifically pharmacology, that refers to a substance or molecule that binds to a receptor and activates it, producing an effect in the body. In other words, an agonist mimics or enhances the action of a naturally occurring substance in the body. This interaction between agonists and receptors is crucial because receptors play a significant role in cellular communication and signal transduction.
When an agonist binds to a receptor, it triggers a series of biochemical reactions that can result in various physiological responses. Depending on the specific receptor being stimulated, the effect produced by the agonist can be diverse and range from beneficial to harmful.
Agonists can be classified into different categories depending on their mechanism of action. For example, a full agonist fully activates a receptor, producing a maximal response. On the other hand, a partial agonist only produces a submaximal response, even though it is binding to the same receptor. Another classification includes agonists that specifically target certain receptor subtypes, allowing for more selective action.
The study and understanding of agonists play a crucial role in pharmacological research and drug development. By identifying potential chemical compounds that can act as agonists, scientists can explore new therapeutic options to treat diseases, alleviate symptoms, or modulate specific physiological functions within the body. The discovery and utilization of agonists in medicine contribute significantly to improving human health and addressing various medical conditions.
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Noting a muscle in a state of contraction, with reference to its opposing muscle, or antagonist.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
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One who contends for the prize in public games.
Etymological and pronouncing dictionary of the English language. By Stormonth, James, Phelp, P. H. Published 1874.
Common Misspellings for AGONIST
Etymology of AGONIST
The word "agonist" originates from the Greek word "ἀγωνιστής" (agonistes), which is derived from the noun "ἀγών" (agon). In ancient Greek, "ἀγών" refers to a competitive contest or struggle, such as a battle, athletic competition, or a verbal debate. The suffix "-istēs" in "ἀγωνιστής" indicates someone who performs or participates in the "ἀγών". Over time, "agonistes" evolved into "agonist" in English, specifically used to describe a chemical substance or drug that interacts with a receptor in the body to produce a specific biological response.
Similar spelling words for AGONIST
- agnostic,
- Aguiniga,
- agonistic,
- agonised,
- agonise,
- agenesia,
- agonus,
- agonized,
- agonising,
- agnostical,
- Against,
- aging,
- Agnus Dei,
- agenesis,
- Agnes,
- Agnus,
- agnise,
- agonize,
- agnosia,
- agonizing,
- agenise.
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