How Do You Spell VALYL TRNA SYNTHETASE?

Pronunciation: [vˈalɪl tˈiː ˌɑːɹˌɛnˈe͡ɪ sˈɪnθɪtˌe͡ɪs] (IPA)

Valyl tRNA Synthetase is spelled "ˈvælɪl tiːɑːrɛneɪ sɪnθəseɪz" in IPA phonetic transcription. The first two syllables "val-" are pronounced with a short "a" sound followed by a clear "l" sound, while the third syllable "-yl" is pronounced with a long "i" sound and a slight "l" sound. The word "tRNA" is pronounced "tiːɑːrɛneɪ" with a long "i" and a slight stress on the first syllable. The final two syllables "Synthetase" have a pronounced "s" followed by two syllables with a clear "n" sound, a short "th" sound and a stressed "eɪ" vowel.

VALYL TRNA SYNTHETASE Meaning and Definition

1. Valyl tRNA synthetase, also known as valine-tRNA ligase, is an enzyme essential for protein synthesis. It belongs to the family of ligases, specifically those forming carbon-oxygen bonds as acid-D-ribose-phosphate ligases (phosphoric ester linkage) or as acid-ester-lyases (carbon-oxygen lyases). This enzyme catalyzes the reaction between valine and its corresponding transfer RNA (tRNA), specifically tRNAVal, ensuring accurate assembly of proteins during translation.

   The process of protein synthesis involves aminoacylation, where an amino acid is attached to its specific tRNA. Valyl tRNA synthetase plays a crucial role in this step by selecting and binding valine, an essential amino acid, and attaching it to the appropriate tRNA molecule. This reaction occurs in the cytoplasm of cells and requires ATP as a source of energy.

   Valyl tRNA synthetase is highly specific for valine, ensuring fidelity in protein synthesis. It recognizes and binds both valine and tRNAVal with high affinity, promoting the formation of a stable valyl-tRNA complex. This complex is subsequently utilized by the ribosome during the elongation phase of protein synthesis.

   Malfunctions or deficiencies in valyl tRNA synthetase can lead to errors in protein synthesis, resulting in cellular dysfunction or diseases such as Valyl-tRNA synthetase deficiency or Charcot-Marie-Tooth disease. Thus, this enzyme plays a crucial role in maintaining proper cellular function and contributing to the overall health and functioning of an organism.

Common Misspellings for VALYL TRNA SYNTHETASE

• calyl trna synthetase
• balyl trna synthetase
• galyl trna synthetase
• falyl trna synthetase
• vzlyl trna synthetase
• vslyl trna synthetase
• vwlyl trna synthetase
• vqlyl trna synthetase
• vakyl trna synthetase
• vapyl trna synthetase
• vaoyl trna synthetase
• valtl trna synthetase
• valgl trna synthetase
• valhl trna synthetase
• valul trna synthetase
• val7l trna synthetase
• val6l trna synthetase
• valyk trna synthetase
• valyp trna synthetase
• valyo trna synthetase