V ABL ONCOGENE Meaning and
Definition
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The term "v abl Oncogene" refers to an oncogene known as the "v-abl Abelson murine leukemia viral oncogene homolog 1". It is a proto-oncogene that was first discovered in the Abelson murine leukemia virus (A-MuLV), a retrovirus that causes leukemia in mice. The "v abl" in the name stands for "viral Abelson" to indicate its origin and connection to the A-MuLV.
The v abl Oncogene is a mutated form of the Abelson gene that has acquired the ability to promote uncontrolled cellular growth and division, leading to the development of cancer. When this oncogene is expressed in cells, it serves as a signaling molecule that triggers excessive and abnormal cell proliferation. It encodes for a protein tyrosine kinase enzyme that is involved in regulating various cellular processes such as cell growth, differentiation, and survival.
The aberrant activation of the v abl Oncogene is associated with the development of certain types of leukemia and other malignancies, both in animals and humans. Studies have shown that mutations or chromosomal translocations involving the Abelson gene can lead to the oncogenic activation of v abl. The abnormal activation of this oncogene disrupts normal cellular control mechanisms and can result in the formation of tumors.
Understanding the mechanisms of oncogene activation, such as v abl, plays a crucial role in cancer research and the development of targeted therapies aimed at inhibiting oncogenic signaling pathways. By targeting and blocking the activity of v abl, it may be possible to halt the excessive cellular proliferation and potentially treat or prevent certain types of cancer.
Common Misspellings for V ABL ONCOGENE
- c abl oncogene
- b abl oncogene
- g abl oncogene
- f abl oncogene
- v zbl oncogene
- v sbl oncogene
- v wbl oncogene
- v qbl oncogene
- v avl oncogene
- v anl oncogene
- v ahl oncogene
- v agl oncogene
- v abk oncogene
- v abp oncogene
- v abo oncogene
- v abl incogene
- v abl kncogene
- v abl lncogene
- v abl pncogene
- v abl 0ncogene
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