V ABL GENE Meaning and
Definition
-
The term "v abl gene" refers to a specific gene that codes for a protein called Abelson tyrosine kinase (ABL). The v abl gene is a version of the abl gene that has been modified or derived from a retrovirus, specifically the Abelson murine leukemia virus (AMuLV).
The v abl gene is commonly used in molecular biology research and is particularly notable for its involvement in the study of cancer and cell signaling pathways. The protein encoded by this gene, ABL, is a tyrosine kinase, which means it adds phosphate groups to tyrosine residues of other proteins, thereby modifying their activity and playing a critical role in cell growth, differentiation, and survival.
The v abl gene gained significant attention in the 1970s and 1980s due to its identification as the transforming oncogene responsible for the development of chronic myelogenous leukemia (CML) and acute lymphoblastic leukemia (ALL) in animal models. The oncogenic potential of the v abl gene results from the constitutive activation of ABL tyrosine kinase, which leads to uncontrolled cell proliferation.
Today, the v abl gene continues to be an important tool in molecular biology, serving as a model for studying protein kinases, signal transduction pathways, and the development of targeted therapies for certain cancers. By understanding the function and regulation of the v abl gene and its protein product, researchers aim to gain valuable insights into the molecular mechanisms of normal and pathological cellular functions.
Common Misspellings for V ABL GENE
- v zbl gene
- v sbl gene
- v wbl gene
- v qbl gene
- v avl gene
- v anl gene
- v ahl gene
- v agl gene
- v abk gene
- v abp gene
- v abo gene
- v abl fene
- v abl vene
- v abl bene
- v abl hene
- v abl yene
- v abl tene
- v abl gwne
- v abl gsne
- v abl gdne
Infographic
Add the infographic to your website:
