How Do You Spell TUMOR SUPPRESSOR?

Pronunciation: [tjˈuːmə səpɹˈɛsə] (IPA)

The spelling of the word "tumor suppressor" can be challenging due to its unusual combination of phonemes. The word is pronounced /ˈtuːmər səˈpresər/ (TOO-mer suh-PRESS-er), with the stress on the second syllable. The first syllable is pronounced as in "too" /tu/, followed by the combination of phonemes /mər/, representing the sounds of "m" and "schwa". The second syllable contains the long sound of the vowel "u" /uː/ and a combination of sounds /səˈpresər/, representing the "s", "schwa", "p", "r", "e", "s", and "er" sounds.

TUMOR SUPPRESSOR Meaning and Definition

1. A tumor suppressor refers to a class of genes that play a crucial role in preventing the formation and progression of cancer. Also known as anti-oncogenes, tumor suppressor genes regulate cellular growth and division by inhibiting the potential formation of tumors. When functioning correctly, these genes help maintain the integrity of the genome by controlling cell cycle checkpoints and repairing DNA damage. Essentially, tumor suppressors act as guardians of the cell, protecting against abnormal cell division and the development of cancerous cells.

   In normal circumstances, tumor suppressor genes act by either preventing the progression of the cell cycle or promoting cell death (apoptosis) when genetic abnormalities are detected. However, mutations or deletions within these genes can disrupt their normal functions, leading to the unchecked growth of cells and the formation of tumors. Consequently, individuals with dysfunctional tumor suppressor genes are at a higher risk of developing cancer.

   Tumor suppressors are diverse and involve various molecular pathways within the cell, such as DNA repair, cell cycle regulation, and apoptosis. Some well-known examples of tumor suppressor genes include TP53 (p53), BRCA1, BRCA2, and APC. Mutations in these genes often predispose individuals to specific types of cancer. Consequently, studying and understanding these genes have been crucial in identifying hereditary cancer syndromes and developing targeted treatments.

   Overall, tumor suppressors act as a powerful defense mechanism against cancer development and progression, making them essential components of cellular homeostasis and safeguarding against the potentially harmful consequences of abnormal cellular growth.

Common Misspellings for TUMOR SUPPRESSOR

• rumor suppressor
• fumor suppressor
• gumor suppressor
• yumor suppressor
• 6umor suppressor
• 5umor suppressor
• tymor suppressor
• thmor suppressor
• tjmor suppressor
• timor suppressor
• t8mor suppressor
• t7mor suppressor
• tunor suppressor
• tukor suppressor
• tujor suppressor
• tumir suppressor
• tumkr suppressor
• tumlr suppressor
• tumpr suppressor
• tum0r suppressor

Etymology of TUMOR SUPPRESSOR

The word "tumor suppressor" is composed of two main components: "tumor" and "suppressor".

1. Tumor: The word "tumor" originated from the Latin word "tumor" meaning "swelling" or "mass". It was derived from the verb "tumere", meaning "to swell". In the medical context, it refers to an abnormal and uncontrolled growth of cells in the body.

2. Suppressor: The word "suppressor" comes from the Latin word "supprimere" which means "to press down" or "to restrain". It is a combination of the prefix "sub-" meaning "under" and the verb "premere" meaning "to press". In the context of genetics and cancer, a tumor suppressor gene refers to a gene that helps regulate cell division and prevents the formation of tumors by suppressing or inhibiting cell growth.

Plural form of TUMOR SUPPRESSOR is TUMOR SUPPRESSORS