Tuberculinization is a medical term used to describe the process of testing for tuberculosis. The pronunciation of this word is tuh-bur-kyoo-luh-nuh-zey-shuhn, with the emphasized syllables being bur, kyo, and nuh. The spelling of this word is based on Latin roots, with tubercul- meaning "tubercle" and -inization meaning "to make into". The use of the letter "c" in tubercul- reflects the Latin pronunciation of "k" sound, while the "z" in -inization reflects the change from "s" to "z" that occurs in many English words when adding the suffix -ize.
Tuberculinization refers to the process of administering a substance called tuberculin to an individual as a diagnostic test for tuberculosis (TB). Tuberculin is derived from the Mycobacterium tuberculosis bacteria, which is the causative agent of TB.
The test involves the injection of a small amount of purified tuberculin beneath the skin, usually on the forearm. After the injection, the area is observed for a localized reaction, commonly known as a tuberculin skin test (TST) or Mantoux test. The response to the tuberculin is interpreted based on the measurement of the resulting swelling or induration.
Tuberculinization is used as a screening tool to identify individuals who have been exposed to the tuberculosis bacteria. It detects the delayed hypersensitivity response of the immune system to the tuberculin antigen. A positive reaction indicates that the individual has been sensitized to tuberculosis, but it does not confirm an active infection. Further evaluation, such as chest X-rays or sputum tests, is usually necessary to diagnose active tuberculosis.
The purpose of tuberculinization is to identify individuals who are at risk of developing active tuberculosis or who may transmit the infection to others. It plays a crucial role in the early detection and prevention of tuberculosis, allowing for timely treatment and control measures.
Treatment of tuberculosis by tuberculin.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "tuberculinization" is derived from "tuberculin", which in turn is derived from "tuberculosis". "Tuberculosis" is comprised of the Latin word "tuberculum", meaning "small swelling or bump", and the suffix "-osis", indicating a state or condition. Therefore, "tuberculosis" refers to the disease characterized by the formation of small nodules or bumps. "Tuberculin" specifically refers to the protein derived from the tuberculosis bacteria (Mycobacterium tuberculosis). When the term "tuberculin" is combined with the suffix "-ization", it creates the word "tuberculinization", which describes the process of testing for tuberculosis by administering a small quantity of tuberculin protein into the skin and observing the reaction.