TOLAZAMIDE Meaning and
Definition
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Tolazamide is a pharmaceutical drug that falls under the category of oral hypoglycemic agents, specifically sulfonylureas, used in the treatment of type 2 diabetes mellitus. It functions by stimulating the pancreas to produce more insulin, which helps in regulating blood sugar levels in the body.
Tolazamide is typically administered orally in the form of tablets. It is rapidly absorbed by the gastrointestinal tract, and its peak effects are usually observed within 2 to 4 hours after ingestion. The drug is metabolized in the liver and excreted primarily through the kidneys.
The primary therapeutic effect of tolazamide is to lower blood glucose levels. It achieves this by increasing insulin secretion and improving the sensitivity of peripheral tissues to insulin action. By doing so, it aids in controlling hyperglycemia and preventing complications arising from glucose intolerance.
As with any medication, tolazamide may have side effects, including hypoglycemia (low blood sugar), gastrointestinal disturbances, skin allergies, and rarely, severe liver toxicity. It is contraindicated in patients who are allergic to sulfonylurea drugs or have a history of severe liver, kidney, or heart disease.
Tolazamide is often prescribed as part of a comprehensive treatment plan that includes dietary modifications and regular exercise. Close monitoring of blood glucose levels is important, and dosage adjustments may be necessary based on individual response to therapy.
In conclusion, tolazamide is a sulfonylurea oral antidiabetic medication used to manage type 2 diabetes by enhancing insulin secretion and improving peripheral insulin sensitivity, ultimately aiding in the maintenance of blood glucose levels within a normal range.
Common Misspellings for TOLAZAMIDE
- rolazamide
- folazamide
- golazamide
- yolazamide
- 6olazamide
- 5olazamide
- tilazamide
- tklazamide
- tllazamide
- tplazamide
- t0lazamide
- t9lazamide
- tokazamide
- topazamide
- tooazamide
- tolzzamide
- tolszamide
- tolwzamide
- tolqzamide
Etymology of TOLAZAMIDE
The word "tolazamide" is derived from its chemical structure and nomenclature. It is a compound made up of two main parts: "tol-" and "-amide".
The "tol-" prefix is commonly used in chemistry to indicate a substitution of the methyl (CH3) group on a benzene ring. In this case, it refers to the presence of a toluene moiety in the molecular structure.
The "-amide" suffix denotes the presence of an amide functional group (-CONH2), which is a compound formed from the reaction of a carboxylic acid with ammonia or an amine.
Therefore, "tolazamide" describes a compound that includes a toluene substituent and an amide functional group in its chemical structure.
