The word "tolamine" is spelled as /təʊləmiːn/. It is a chemical compound used as a vasodilator and anesthetic. The first syllable is pronounced as "t-oh" with the vowel sound of "o" in "go". The second syllable is pronounced as "luh" with the vowel sound of "u" in "up". The third syllable is pronounced as "m-ih-n" with the ending vowel sound of "i" in "kit". The stress is on the second syllable. When pronouncing "tolamine", it is important to place emphasis on the second syllable and pronounce each syllable distinctly.
Tolamine is a chemical compound with pharmaceutical properties that belong to the class of sympatholytic drugs. It acts as a reversible antagonist of alpha-adrenergic receptors, primarily targeting the alpha-2 subtype. This means that tolamine can competitively bind to these receptors, preventing the action of norepinephrine or other similar substances that activate them. By inhibiting the response of alpha-2 receptors, tolamine exerts a sympatholytic effect on the body.
Tolamine is commonly used in medicine for its vasodilatory properties. By blocking alpha-2 adrenoceptors found in smooth muscles surrounding blood vessels, tolamine causes relaxation of these muscles, resulting in the dilation of blood vessels. This pharmacological action allows for increased blood flow and decreased peripheral vascular resistance, leading to reduced blood pressure.
Additionally, tolamine has shown efficacy in certain local anesthetic solutions. Its vasoconstrictive properties make it a useful additive to local anesthetics, minimizing blood flow at the injection site and prolonging the duration of anesthesia.
While generally safe, tolamine may have potential side effects such as dizziness, headache, or orthostatic hypotension. As with any medication, its use should be accompanied by proper medical assessment and supervision to determine the appropriate dose and administration route for each patient.
Chloramine-T.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "tolamine" is a chemical compound name, specifically a generic name for a drug called "isosorbide mononitrate". The etymology of the word "tolamine" is derived from its chemical structure and naming conventions.
The prefix "tol-" in "tolamine" likely comes from the chemical compound called "toluene", which is a hydrocarbon derivative of benzene. Toluene is commonly used as a solvent and has various applications in the chemical industry.
The "-amine" suffix in "tolamine" indicates the presence of an amino group (-NH2) in the chemical structure. "Amine" is a common suffix used to denote organic compounds that contain nitrogen atoms.
Overall, the word "tolamine" is derived from the combination of the term "toluene" and the suffix "-amine", representing the specific chemical structure and functional group present in the compound.