Tissue Polypeptide Antigen (TPA) is a term used in medical and biological sciences to describe a specific type of antigen that is synthesized in human tissues. It refers to a group of polypeptide antigens present in various types of tissues, particularly in epithelial cells.
TPA is commonly used as a marker to detect and monitor the presence of cancerous cells in the body, particularly in cases of carcinomas. Elevated levels of TPA in the blood can indicate the presence and progression of certain types of cancers, such as ovarian, lung, breast, and gastrointestinal cancers.
The levels of TPA are measured through a blood test called Tissue Polypeptide-Specific Antigen (TPS). This test is often used in conjunction with other diagnostic methods to assess the effectiveness of cancer treatment, monitor recurrence of cancer, and track the overall progression of the disease.
The TPA antigen is produced by healthy cells as well, and its levels can vary depending on factors like age, menstrual cycle, and hormonal imbalances. However, significantly elevated levels of TPA often correlate with cancerous cell growth and invasion.
Overall, Tissue Polypeptide Antigen is an essential biomarker used in the field of oncology to aid in the diagnosis and management of cancer. Its detection and quantification can provide valuable information for clinicians, helping them make informed decisions regarding treatment and prognosis.
