TISSUE KALLIKREIN Meaning and
Definition
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Tissue kallikrein is a proteolytic enzyme that belongs to the family of serine proteases. It is primarily found within tissues, particularly in the kidneys, salivary glands, and pancreas. Tissue kallikrein plays a vital role in various physiological processes, including blood pressure regulation, inflammation, and tissue repair.
The enzyme is involved in the conversion of kininogen to bradykinin, a potent vasodilator peptide. By generating bradykinin, tissue kallikrein promotes the relaxation of blood vessels, leading to a decrease in blood pressure. This function is important in the maintenance of cardiovascular homeostasis.
In addition, tissue kallikrein demonstrates anti-inflammatory properties. It can degrade certain proinflammatory mediators, such as complement factors and fibrinogen, thereby suppressing the inflammatory response. This enzyme also participates in the regulation of immune cell activation and migration, contributing to the modulation of inflammation.
Furthermore, tissue kallikrein is implicated in tissue repair and regeneration. Through its proteolytic activity, it contributes to the breakdown and remodeling of extracellular matrix components, facilitating tissue remodeling and wound healing processes.
Overall, tissue kallikrein is a multifunctional enzyme involved in several physiological processes, including blood pressure regulation, inflammation, and tissue repair. Its diverse functions make it an important target for therapeutic interventions aimed at treating various cardiovascular, inflammatory, and tissue-related disorders.
Common Misspellings for TISSUE KALLIKREIN
- rissue kallikrein
- fissue kallikrein
- gissue kallikrein
- yissue kallikrein
- 6issue kallikrein
- 5issue kallikrein
- tussue kallikrein
- tjssue kallikrein
- tkssue kallikrein
- tossue kallikrein
- t9ssue kallikrein
- t8ssue kallikrein
- tiasue kallikrein
- tizsue kallikrein
- tixsue kallikrein
- tidsue kallikrein
- tiesue kallikrein
- tiwsue kallikrein
- tisaue kallikrein
- tiszue kallikrein
Etymology of TISSUE KALLIKREIN
The word "Tissue Kallikrein" is derived from two main components: "tissue" and "kallikrein".
1. Tissue: The term "tissue" comes from the Latin word "tessera", meaning a small piece or portion. In biology, "tissue" refers to a group of cells that perform a similar function or work together to perform a specific task in an organism.
2. Kallikrein: "Kallikrein" is derived from the Greek words "kalli" meaning beautiful or handsome, and "kreas" meaning flesh or meat. The term was coined by Swedish physiologist Ulf von Euler while studying the pancreas. He named it kallikrein due to its ability to produce a beautiful or sweet-smelling substance when it comes in contact with tissue.
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