TISSUE DISTRIBUTIONS Meaning and
Definition
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Tissue distribution refers to the process by which a substance, such as a drug or nutrient, is spread or dispersed throughout different tissues in an organism. It describes the location and concentration of the substance within various organs, tissues, and cells of the body.
In pharmacology, tissue distribution is a critical aspect to consider when studying drug effects and determining the drug's effectiveness. Different drugs have varying capacities to penetrate different tissues and accumulate at specific sites in the body. Understanding tissue distribution is important to ensure that drugs reach their target tissues to exert their intended therapeutic effects.
Tissue distribution is influenced by various factors including molecular size, lipophilicity (affinity for lipid molecules), blood flow, and the presence of specific transport proteins. For instance, lipophilic drugs can easily pass through lipid membranes and distribute throughout fatty tissues. Moreover, the blood supply to different tissues can affect drug distribution, as organs with high blood flow, such as the liver and kidneys, tend to receive larger amounts of circulating drugs.
The study of tissue distribution also plays a crucial role in understanding disease pathogenesis and the development of targeted therapies. It helps determine which tissues or organs are primarily affected by a disease and guides the design of drugs that preferentially accumulate in the affected tissues.
Overall, tissue distribution is a fundamental concept in pharmacology and biomedical research, providing valuable insights into the movement of substances within the body and aiding in the development and proper utilization of therapeutic interventions.
Common Misspellings for TISSUE DISTRIBUTIONS
- rissue distributions
- fissue distributions
- gissue distributions
- yissue distributions
- 6issue distributions
- 5issue distributions
- tussue distributions
- tjssue distributions
- tkssue distributions
- tossue distributions
- t9ssue distributions
- t8ssue distributions
- tiasue distributions
- tizsue distributions
- tixsue distributions
- tidsue distributions
- tiesue distributions
- tiwsue distributions
- tisaue distributions
- tiszue distributions
Etymology of TISSUE DISTRIBUTIONS
The word "tissue" originates from the Latin word "texere" meaning "to weave". In its original sense, "tissue" referred to a woven fabric. In the late medieval period, the term began to be used to describe the woven structure of animal and plant organs, leading to its modern usage in biology to refer to groups of cells that perform a similar function.
"Distribution" comes from the Latin word "distributio", which means "a dividing up" or "a giving out". It is derived from the verb "distribuere" which means "to distribute" or "to divide". In this context, "distribution" refers to the spreading or allocation of something, in this case, the spreading of tissues throughout an organism.
Therefore, the term "tissue distributions" refers to the spread or allocation of different types of tissues within an organism.
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