How Do You Spell THYROGLOBULIN?

Pronunciation: [θˈa͡ɪɹəɡlˌɒbjʊlˌɪn] (IPA)

Thyroglobulin is a medical term used to describe a protein that is synthesized by the thyroid gland. The word can be broken down into four syllables, with the stress falling on the third syllable. The initial "th" sound is pronounced as in the word "thin," followed by the "ah" sound as in "father." The "yro" sound is pronounced like the word "year," while the final "bulin" sounds like "bool-in." The IPA phonetic transcription for thyroglobulin is θaɪrəʊˈɡlɒbjʊlɪn.

THYROGLOBULIN Meaning and Definition

1. Thyroglobulin is a glycoprotein that is a key component of the thyroid gland's colloidal material. It is primarily produced and secreted by the follicular cells of the thyroid gland, which is responsible for the production and regulation of thyroid hormones. Thyroglobulin serves as a precursor for the synthesis of the two major thyroid hormones, triiodothyronine (T3) and thyroxine (T4).

   In the process of hormone synthesis, thyroglobulin is transported into the follicular lumen of the thyroid gland. Within the follicular lumen, thyroglobulin is enzymatically cleaved by the action of thyroid peroxidase and hydrogen peroxide, resulting in the release of T3 and T4. These thyroid hormones play crucial roles in regulating various physiological processes in the body, including metabolism, growth, development, and energy production.

   Measurement of thyroglobulin levels in the blood can provide valuable information regarding the function of the thyroid gland. Increased levels of thyroglobulin in the blood may indicate various conditions such as thyroid cancer, Graves' disease, or Hashimoto's thyroiditis. Conversely, decreased levels of thyroglobulin could suggest an underactive thyroid (hypothyroidism). Thus, thyroglobulin serves as a biomarker for the evaluation and diagnosis of thyroid-related disorders.

   In summary, thyroglobulin is a protein synthesized and secreted by the thyroid gland, important for the production of thyroid hormones. Its measurement can aid in diagnosing and monitoring thyroid-related conditions.

2. An iodine-containing globulin in the thyroid gland.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for THYROGLOBULIN

• rhyroglobulin
• fhyroglobulin
• ghyroglobulin
• yhyroglobulin
• 6hyroglobulin
• 5hyroglobulin
• tgyroglobulin
• tbyroglobulin
• tnyroglobulin
• tjyroglobulin
• tuyroglobulin
• tyyroglobulin
• thtroglobulin
• thgroglobulin
• thhroglobulin
• thuroglobulin
• th7roglobulin
• th6roglobulin
• thyeoglobulin

Etymology of THYROGLOBULIN

The word "thyroglobulin" has its origins in the combination of two terms: "thyro" and "globulin".

1. "Thyro": This refers to the thyroid gland, which is a small, butterfly-shaped gland in the neck responsible for producing thyroid hormones. The term comes from the Greek word "thyreos" meaning "shield" (referring to the shape of the gland).

2. "Globulin": This is a type of protein found in the blood plasma. The term "globulin" is derived from the Latin word "globus", meaning "ball" or "sphere". It refers to the globular shape of many proteins.

When these two terms are combined, "thyroglobulin" refers to a specific protein that is synthesized by the thyroid gland and stored within it.