THROMBASTHENIA Meaning and
Definition
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Thrombasthenia is a medical condition characterized by an abnormality in the function or quantity of platelets, which are specialized blood cells responsible for clotting. This condition can be inherited or acquired, and it leads to various bleeding problems due to the impaired ability of platelets to form and stabilize blood clots.
In thrombasthenia, the platelets lack or have reduced levels of glycoprotein IIb/IIIa on their surface. This glycoprotein plays a crucial role in platelet activation and aggregation, as it serves as a receptor for fibrinogen, von Willebrand factor, and other molecules involved in clot formation. As a result, the platelets' ability to bind to these proteins and form stable clots is compromised.
Common symptoms of thrombasthenia include easy bruising, nosebleeds, prolonged bleeding after injury or surgery, and heavy or prolonged menstrual periods in women. In severe cases, spontaneous bleeding may occur, and internal bleeding can become life-threatening.
To diagnose thrombasthenia, medical professionals often perform a range of tests such as platelet aggregometry, flow cytometry, and genetic testing to determine the underlying cause and severity of the condition.
Treatment for thrombasthenia typically involves managing bleeding episodes with blood transfusions or platelet transfusions, the use of medications to promote clot formation, and in some cases, bone marrow transplantation. Regular monitoring and close follow-up with a hematologist are essential for patients with thrombasthenia to ensure appropriate management and prevent complications associated with excessive bleeding.
Common Misspellings for THROMBASTHENIA
- rhrombasthenia
- fhrombasthenia
- ghrombasthenia
- yhrombasthenia
- 6hrombasthenia
- 5hrombasthenia
- tgrombasthenia
- tbrombasthenia
- tnrombasthenia
- tjrombasthenia
- turombasthenia
- tyrombasthenia
- theombasthenia
- thdombasthenia
- thfombasthenia
- thtombasthenia
- th5ombasthenia
- th4ombasthenia
- thrimbasthenia
Etymology of THROMBASTHENIA
The word "thrombasthenia" is derived from two Greek roots: "thrombo" meaning "clot" or "thrombus" and "asthenia" meaning "weakness" or "lack of strength". Therefore, "thrombasthenia" can be understood to mean a condition characterized by the weakness or lack of strength in blood clots or thrombi.
Similar spelling words for THROMBASTHENIA
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