Thogoto like virus (TLV) is a member of the Bunyaviridae family, specifically belonging to the genus Orthobunyavirus. It is an arbovirus, which means it is transmitted by arthropods such as ticks or mosquitoes. TLV was first isolated in Thogoto, a small village in Kenya, and it is named after this locality.
TLV is primarily found in East Africa, particularly in Kenya, Uganda, and Tanzania. However, it has been detected in other countries as well, including Saudi Arabia and Pakistan. The natural reservoirs of TLV are not well-established, but it is believed that birds and small mammals may play a role in maintaining the virus.
In humans, TLV infection can lead to a febrile illness characterized by symptoms such as fever, headache, muscle and joint pain, and fatigue. In some cases, it can progress to more severe manifestations, such as meningitis or encephalitis, which may result in neurological complications. However, TLV infections in humans appear to be relatively rare.
The diagnosis of TLV infection is based on laboratory testing, specifically serological assays that detect the presence of antibodies against the virus in the patient's blood. There is currently no specific treatment or vaccine available for TLV, and management relies on supportive care to alleviate symptoms.
Overall, Thogoto like virus is a zoonotic virus that is typically transmitted to humans through arthropod vectors. While it can cause illness in humans, TLV infections are generally sporadic and not widely reported.
