THIOPHOSPHAMIDE Meaning and
Definition
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Thiophosphamide is a chemical compound that falls under the category of organophosphorus compounds. It is derived from the parent compound, phosphoramide, by substituting an oxygen atom with a sulfur atom in the structural formula. This substitution results in the formation of a thiophene ring, giving the compound its distinctive name.
Thiophosphamide is commonly used as a pharmaceutical agent in the field of cancer chemotherapy. It belongs to a class of drugs known as alkylating agents, which work by damaging the DNA of cancer cells, thereby inhibiting their ability to multiply and spread. This compound specifically targets and reacts with the guanine bases within the DNA molecule, causing the DNA strands to cross-link. The cross-linking prevents DNA replication and transcription, leading to cell death and reduced tumor growth.
Apart from its anti-cancer properties, thiophosphamide exhibits immunosuppressive effects. It can be utilized to prevent the rejection of transplanted organs by suppressing the immune response of the recipient. This is achieved by inhibiting the production of lymphocytes and T-cells, which are responsible for immune reactions.
When used therapeutically, thiophosphamide is typically administered intravenously or orally. It is known to have a variety of side effects, including nausea, vomiting, bone marrow suppression, and an increased susceptibility to infections. Regular monitoring of blood cell counts is essential during treatment to manage these side effects.
In summary, thiophosphamide is an organophosphorus compound used in chemotherapy for the treatment of cancer. It functions by damaging the DNA of cancer cells, thereby inhibiting their replication and growth. Additionally, it possesses immunosuppressive properties and can be used to prevent organ rejection in transplant patients.
Common Misspellings for THIOPHOSPHAMIDE
- rhiophosphamide
- fhiophosphamide
- ghiophosphamide
- yhiophosphamide
- 6hiophosphamide
- 5hiophosphamide
- tgiophosphamide
- tbiophosphamide
- tniophosphamide
- tjiophosphamide
- tuiophosphamide
- tyiophosphamide
- thuophosphamide
- thjophosphamide
- thkophosphamide
- thoophosphamide
- th9ophosphamide
- th8ophosphamide
- thiiphosphamide
- thikphosphamide
Etymology of THIOPHOSPHAMIDE
The word "Thiophosphamide" is a compound word derived from two components: "thio-" and "phosphamide".
1. "Thio-" is a prefix derived from the Greek word "theîon" meaning sulfur. In chemistry, this prefix is used to indicate the presence of a sulfur atom or sulfur-containing group in a compound.
2. "Phosphamide" is a compound suffix derived from "phosphorus" and "amide". "Phosphorus" is derived from the Greek word "phosphoros", meaning "light-bringing". "Amide" is derived from the Latin word "amidus", meaning ammonia. In chemistry, an amide refers to a compound derived from ammonia where one or more hydrogen atoms are replaced by acyl groups (RCONR2).
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