THIMETHAPHAN Meaning and
Definition
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Thimethaphan is a pharmacological agent that is commonly referred to as ganglionic blocker. It is classified as a quaternary ammonium compound and belongs to the class of drugs known as antihypertensives. Thimethaphan exerts its therapeutic effects by inhibiting the transmission of nerve impulses in the autonomic ganglia, ultimately leading to a decreased sympathetic outflow.
The drug acts by competitively blocking the nicotinic receptors located on the postganglionic neurons throughout the autonomic nervous system. By doing so, Thimethaphan prevents the binding of acetylcholine, the neurotransmitter responsible for transmitting impulses, to these receptors. Consequently, the function of the sympathetic nervous system, which is responsible for initiating the "fight or flight" response, is inhibited.
Thimethaphan is primarily used clinically in the management of hypertensive emergencies such as severe hypertension. It rapidly produces a significant reduction in blood pressure by blocking sympathetic nerve impulses and allowing for vasodilation, relaxation of smooth muscles, and decreased cardiac output. However, its therapeutic use has significantly declined in recent years due to the development of alternative and more potent antihypertensive agents.
Despite its effectiveness in managing hypertensive emergencies, Thimethaphan has several adverse effects that limit its use. These include postural hypotension, blurred vision, dry mouth, gastrointestinal disturbances, and urinary retention. Moreover, it has a short duration of action, requiring frequent dosing or continuous infusion to maintain its pharmacological effects.
Common Misspellings for THIMETHAPHAN
- rhimethaphan
- fhimethaphan
- ghimethaphan
- yhimethaphan
- 6himethaphan
- 5himethaphan
- tgimethaphan
- tbimethaphan
- tnimethaphan
- tjimethaphan
- tuimethaphan
- tyimethaphan
- thumethaphan
- thjmethaphan
- thkmethaphan
- thomethaphan
- th9methaphan
- th8methaphan
- thinethaphan
- thikethaphan
Etymology of THIMETHAPHAN
The word "Thimethaphan" is a pharmaceutical drug, also known by its generic name Ganglionic Blocking Agent. As a drug name, "Thimethaphan" is a coined term without a specific etymology. It is typically composed of syllables or letters that have no direct linguistic meaning but are selected for branding and trademark purposes. The naming conventions for pharmaceutical drugs often involve combining various elements such as sound, ease of pronunciation, or association with the therapeutic purpose, while complying with regulatory and trademark requirements.
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