TELOMERIZATION Meaning and
Definition
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Telomerization is a chemical process that involves the addition of telomeric units, also known as telomers, to the ends of a molecular chain. Telomers are repetitive sequences of nucleotides, usually consisting of DNA or RNA, that act as protective caps on the ends of chromosomes. This process helps to maintain the integrity and stability of the genome.
In telomerization, telomers are added to the ends of molecules through the action of telomerase enzymes. Telomerase is an enzyme that synthesizes telomeric DNA sequences by using an RNA template. This allows the telomeres to be extended and replenished when they are shortened during DNA replication. By adding telomers, telomerization prevents the loss of valuable genetic information and ensures the proper functioning of cells.
Telomerization is of significant importance in biological systems as it plays a crucial role in aging and the development of certain illnesses. In normal human cells, telomeres progressively shorten over time, leading to cellular senescence and eventual cell death. On the other hand, telomerization is observed in cancer cells, enabling them to replicate indefinitely and proliferate uncontrollably.
Outside of biology, the term "telomerization" also finds applications in chemistry and polymer science. In these contexts, it refers to the process of adding telomeric units to the ends of polymer chains to modify their properties, such as increasing their molecular weight or altering their reactivity. This technique is commonly employed in the synthesis of specialized materials with desired properties for various industrial applications.
Common Misspellings for TELOMERIZATION
- relomerization
- felomerization
- gelomerization
- yelomerization
- 6elomerization
- 5elomerization
- twlomerization
- tslomerization
- tdlomerization
- trlomerization
- t4lomerization
- t3lomerization
- tekomerization
- tepomerization
- teoomerization
- telimerization
- telkmerization
- tellmerization
- telpmerization
- tel0merization
Etymology of TELOMERIZATION
The word "telomerization" is derived from two key components: "telomere" and the suffix "-ization".
The term "telomere" was coined by Hermann Muller in 1938, derived from the Greek words "telos" meaning "end" and "meros" meaning "part". Telomeres are the protective caps found at the ends of chromosomes, composed of repetitive nucleotide sequences.
The suffix "-ization" is a common suffix in the English language that signifies the process of making or becoming something. It is derived from the Greek suffix "-izein" or "-izo", indicating the act or result of a process.
When combined, "telomerization" refers to the process of manipulating or modifying telomeres. It typically involves the addition or removal of nucleotide sequences from telomeres, often facilitated by enzymes.
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