TCR BETA GENE Meaning and
Definition
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The TcR beta gene, also known as the T-cell receptor beta gene, is a gene that encodes the beta chain of the T-cell receptor (TcR) protein. TcR is a protein complex found on the surface of T-cells, which are a type of white blood cell involved in the immune response. T-cells play a crucial role in the adaptive immune system, recognizing and responding to specific antigens.
The TcR beta gene is located on one of the T-cell receptor gene clusters, usually on chromosome 7 in humans. It consists of a series of exons that are transcribed and translated to produce the TcR beta chain. The TcR beta chain combines with the alpha chain to form a heterodimeric TcR complex, which recognizes antigens presented by major histocompatibility complex molecules on the surface of other cells.
The TcR beta gene exhibits a high degree of genetic diversity due to a process known as V(D)J recombination. This process involves the rearrangement of gene segments called variable (V), diversity (D), and joining (J) segments, resulting in the generation of a diverse repertoire of TcR beta chains capable of recognizing a wide range of antigens.
Mutations or alterations in the TcR beta gene can lead to immune deficiencies or dysregulation of the immune response. Therefore, understanding the structure and function of the TcR beta gene is crucial for unraveling the mechanisms of T-cell mediated immunity and potentially developing new strategies for diagnosis and treatment of immune disorders.
Common Misspellings for TCR BETA GENE
- rcr beta gene
- fcr beta gene
- gcr beta gene
- ycr beta gene
- 6cr beta gene
- 5cr beta gene
- txr beta gene
- tvr beta gene
- tfr beta gene
- tdr beta gene
- tce beta gene
- tcd beta gene
- tcf beta gene
- tct beta gene
- tc5 beta gene
- tc4 beta gene
- tcr veta gene
- tcr neta gene
- tcr heta gene
- tcr geta gene
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