How Do You Spell TCR?

Pronunciation: [tˌiːsˌiːˈɑː] (IPA)

The initials TCR often cause confusion when it comes to spelling. The correct way to spell TCR is by simply pronouncing the letters as they are; T-C-R. In IPA phonetic transcription, this would be /tiː siː ɑːr/. It is important to ensure that each letter is pronounced clearly and accurately to avoid any misunderstandings. TCR is an acronym for many terms, including T-cell receptor, Total Customer Return, and Temporary Change Request, among others.

Meaning and Definition
Common Misspellings
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TCR Meaning and Definition

  1. TCR stands for T-cell Receptor. It is a specialized protein receptor found on the surface of T-cells, which are a type of white blood cell involved in the immune system response. The TCR is essential for T-cells to recognize and bind to specific antigen fragments presented by major histocompatibility complex (MHC) molecules on the surface of antigens, such as infected cells or cancer cells.

    The TCR is highly diverse, owing to its ability to recognize a wide range of antigens. It consists of two protein chains, known as alpha and beta chains, which come together to form a complex receptor structure. The alpha and beta chains each contain a variable region that determines the specificity of the TCR for a specific antigen.

    Upon recognition of an antigen-MHC complex, the TCR sends signals to the T-cell, triggering a cascade of immune responses that are vital for the elimination of foreign invaders or abnormal cells. These responses include the activation and proliferation of T-cells, as well as the release of immune mediators that recruit other immune cells to the site of infection or tumor.

    The TCR plays a crucial role in both cell-mediated and humoral immunity. It is a fundamental component of the adaptive immune system, as it allows T-cells to discriminate between self and non-self antigens, ensuring a targeted and specific immune response. Defects or dysregulation of the TCR can lead to immunodeficiency disorders, autoimmunity, or inefficient immune responses.

Common Misspellings for TCR

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Correct spelling for TCR
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