Spindle cell nevi, also known as spindle cell melanocytic nevi or spindle cell nevus, refer to skin growths characterized by the presence of spindle-shaped cells. These nevi are typically benign and do not usually develop into cancerous conditions.
Spindle cells, which are elongated and resemble spindles, are present within the dermal layer of the skin. They are a type of cells that can be found in various tissues of the body. In the case of spindle cell nevi, these cells are derived from melanocytes, which are responsible for the production and distribution of melanin - the pigment responsible for skin, hair, and eye color.
Spindle cell nevi typically appear as raised, smooth, and dome-shaped skin lesions that range in color from pink to brown. They can vary in size, but most often are less than 1 centimeter in diameter. These nevi are commonly found on sun-exposed areas of the skin, such as the face, arms, and legs. They can also occur on mucosal surfaces and within the mouth.
Although spindle cell nevi are generally harmless, they may share some clinical and histological features with malignant melanomas, which are aggressive skin cancers. Therefore, it is essential for a trained healthcare provider or dermatologist to examine these skin lesions and differentiate them from potentially cancerous growths. A biopsy or further diagnostic tests may be necessary to confirm their benign nature.
