Serum folate level refers to the concentration of folate, a B-vitamin, in the liquid component of blood known as serum. Folate is an essential nutrient that plays a crucial role in various biological processes, including DNA synthesis and cell division.
This laboratory parameter is measured to assess the body's folate status, as it provides valuable information regarding the amount of folate available in the blood for various physiological functions. Serum folate level is typically measured using a blood sample collected from a vein, and the concentration is reported in nanograms per milliliter (ng/mL) or micrograms per liter (μg/L).
Abnormal serum folate levels can indicate an individual's nutritional status or potential underlying health conditions. A deficiency of folate in the body, known as folate deficiency, can lead to health issues such as anemia, fatigue, poor growth (in children), and impaired cognitive function. On the other hand, excessively high levels of serum folate, although rare, can be indicative of certain medical conditions or excessive intake of folic acid supplements.
Measuring serum folate levels is especially important during pregnancy, as folate plays a crucial role in fetal development and reduces the risk of neural tube defects. If an individual's serum folate level is found to be low, healthcare providers may recommend dietary changes or prescribe folic acid supplements to restore adequate folate levels. Conversely, if serum folate levels are excessively high, further evaluation may be necessary to identify and manage the underlying cause.
