How Do You Spell SERINE TRANSHYDROXYMETHYLASE?

Pronunciation: [sˈɛɹiːn tɹanʃˈa͡ɪdɹəksˌa͡ɪmθɪlˌe͡ɪs] (IPA)

The spelling of "Serine Transhydroxymethylase" can be confusing, but its pronunciation can be deciphered using IPA phonetic transcription. According to the transcription, the word is pronounced as 'sɛriːn trænzhaɪdrɒksɪˈmɛθɪleɪz'. The word consists of two parts, "serine" and "transhydroxymethylase", with each part having its own distinct pronunciation. Serine is pronounced as 'sɛriːn', and transhydroxymethylase is pronounced as 'trænzhaɪdrɒksɪˈmɛθɪleɪz'. Understanding the IPA transcription can help in correctly spelling and pronouncing difficult scientific terms like this.

SERINE TRANSHYDROXYMETHYLASE Meaning and Definition

1. Serine transhydroxymethylase (SHMT) is an enzyme that plays a vital role in the metabolism of serine, an essential amino acid. This enzyme performs a key reaction called the transhydroxymethylation of serine. This reaction involves the transfer of a hydroxymethyl group (-CH₂OH) from serine to an acceptor molecule, which can be a variety of compounds such as tetrahydrofolate (THF) or glycine. By catalyzing this reaction, SHMT is able to interconvert serine and glycine, two amino acids that are important building blocks for proteins and other biological molecules.

   The main function of SHMT is to maintain the balance of serine and glycine in the body, ensuring an adequate supply of both amino acids for various biological processes. In addition to its role in amino acid metabolism, SHMT also participates in the one-carbon metabolism pathway, which is critical for the synthesis of nucleotides, methionine, and other important molecules. This pathway involves the transfer of one-carbon units between different compounds, and SHMT provides a key link between serine and the one-carbon metabolism pathway.

   Serine transhydroxymethylase is found in many different tissues and organs, including the liver, kidneys, brain, and red blood cells. Mutations or dysregulation of SHMT can lead to several metabolic disorders, including hyperhomocysteinemia and various forms of neural tube defects. As a result, SHMT is an important target for therapeutic interventions and a subject of research into understanding the underlying mechanisms of these disorders.

Common Misspellings for SERINE TRANSHYDROXYMETHYLASE

• aerine transhydroxymethylase
• zerine transhydroxymethylase
• xerine transhydroxymethylase
• derine transhydroxymethylase
• eerine transhydroxymethylase
• werine transhydroxymethylase
• swrine transhydroxymethylase
• ssrine transhydroxymethylase
• sdrine transhydroxymethylase
• srrine transhydroxymethylase
• s4rine transhydroxymethylase
• s3rine transhydroxymethylase
• seeine transhydroxymethylase
• sedine transhydroxymethylase
• sefine transhydroxymethylase
• setine transhydroxymethylase
• se5ine transhydroxymethylase
• se4ine transhydroxymethylase
• serune transhydroxymethylase
• serjne transhydroxymethylase

Etymology of SERINE TRANSHYDROXYMETHYLASE

The word "Serine Transhydroxymethylase" is a scientific term composed of two main components: "serine" and "transhydroxymethylase".

1. Serine: The term "serine" is derived from the Latin word "sericum", which means "silk". It was named so because serine was first isolated from silk protein in 1865 by the German chemist Hermann Kolbe. Serine is an amino acid that plays a crucial role in protein synthesis and various metabolic processes in living organisms.

2. Transhydroxymethylase: "Transhydroxymethylase" is a compound term formed by merging two parts: "trans-" and "hydroxymethylase".

- Trans-: The prefix "trans-" derived from Latin means "across" or "on the other side".