The spelling of the word "schizophrene" can be explained using the International Phonetic Alphabet (IPA). The first syllable "schi" is pronounced "ski" like in "skiing," followed by "zo" pronounced "zoh" like in "zoo," and "phrene" pronounced "freen" like in "green." Putting it all together, the proper pronunciation is "ski-zoh-freen." "Schizophrene" is a term used in psychiatry to describe a person with schizophrenia, a severe mental disorder characterized by distorted thinking and perception.