How Do You Spell RIFAMPICIN?

Pronunciation: [ɹˈɪfɐmpˌɪsɪn] (IPA)

Rifampicin is an antibiotic used to treat tuberculosis and other bacterial infections. The spelling of the word can be confusing due to the unusual combination of letters. The IPA phonetic transcription of rifampicin is /ˌrɪfæmˈpaɪsɪn/. The "r" sounds like "ree," while "ifam" is pronounced "ih-fam." The "p" in "picin" is silent, and the word ends with a short "ih" sound. Overall, the spelling and pronunciation of rifampicin require a careful attention to detail to ensure accurate communication in healthcare settings.

RIFAMPICIN Meaning and Definition

1. Rifampicin is an antibiotic drug belonging to the rifamycin class. It is commonly used in the treatment of tuberculosis (TB) and other infections caused by bacteria belonging to the Mycobacterium genus. Rifampicin works by inhibiting the action of RNA polymerase, an enzyme that is crucial for the synthesis of RNA molecules in bacteria.

   The drug is characterized by its broad spectrum of antimicrobial activity. It is highly effective against Mycobacterium tuberculosis, the bacteria responsible for TB, and is an essential component of the standard treatment regimen. Rifampicin is also used in combination with other antibiotics to treat other bacterial infections such as leprosy, legionnaire's disease, and certain types of pneumonia caused by bacteria like Streptococcus pneumoniae.

   Rifampicin is generally administered orally as a tablet or capsule, but it can also be given intravenously in some cases. It is well-absorbed from the gastrointestinal tract and readily distributed throughout the body, including into various body fluids and tissues. The drug is metabolized in the liver and excreted primarily in the bile and feces. It is known to interact with several drugs, including certain antiretrovirals used in the treatment of HIV, and can induce the metabolism of these medications, necessitating dose adjustments.

   Common side effects of rifampicin include gastrointestinal symptoms such as nausea, vomiting, and diarrhea. It may also cause rash, fever, and headache. In rare cases, more severe adverse effects like hepatotoxicity (liver damage) can occur. Due to its potent antimicrobial properties, rifampicin has been a crucial component in the fight against tuberculosis and has significantly contributed to reducing morbidity and mortality associated with the disease.

Common Misspellings for RIFAMPICIN

• eifampicin
• difampicin
• fifampicin
• tifampicin
• 5ifampicin
• 4ifampicin
• rufampicin
• rjfampicin
• rkfampicin
• rofampicin
• r9fampicin
• r8fampicin
• ridampicin
• ricampicin
• rivampicin
• rigampicin
• ritampicin
• rirampicin
• rifzmpicin
• rifsmpicin

Etymology of RIFAMPICIN

The word "rifampicin" is derived from a combination of different elements.

The first part, "rifa-" or "rifo-", is derived from the Rifamycin group of antibiotics, which was originally isolated from a strain of Streptomyces mediterranei found in the Rif Mountains of Morocco. Rifamycins were named after this particular geographical region.

The second part, "-m-", is derived from "medici-" or "medical-", referring to the medical applications of this antibiotic.

Finally, the suffix "-picin" is commonly used in the nomenclature of antibiotics, derived from "picein", a term used in the past to describe bacterial extracts or antisepsis solutions.

Therefore, combining these elements, "rifampicin" refers to an antibiotic from the Rifamycin group that has medical applications.

Plural form of RIFAMPICIN is RIFAMPICINS