RETROPOSED Meaning and
Definition
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Retroposed is an adjective that refers to a genetic sequence or element that has been transposed in the opposite direction within the genome compared to its original orientation. It describes a process where a DNA segment is duplicated and then inserted back into the genome in an inverted or reversed orientation. This phenomenon is commonly observed in genomes, especially in eukaryotes, and is known to contribute to genetic variation and genome evolution.
During retroposition, the duplicated DNA segment, often originating from a gene or a non-coding region, is transcribed into RNA. This RNA is then reverse transcribed back into DNA by the enzyme reverse transcriptase and subsequently integrated back into the genome. As a result, the retroposed DNA segment retains sequence similarity to its original counterpart but is now present in an inverted or reversed orientation.
Retroposed elements can have various effects on genomic function and evolution. They may lead to the creation of new genes, as the reverse transcription process can introduce mutations, gene fusions, or changes in gene expression. Some retroposed elements can also disrupt existing genes, potentially causing disease-causing mutations or alterations in gene regulation.
Overall, retroposition is an essential mechanism that contributes to genetic diversity and the dynamics of genomes. By expanding the range of genetic material available for evolution, retroposed elements play a significant role in shaping the complexity and variability of genomes across different organisms.
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Displaced backward, but not inclined or bent, neither retroverted nor retroflexed.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for RETROPOSED
- eetroposed
- detroposed
- fetroposed
- tetroposed
- 5etroposed
- 4etroposed
- rwtroposed
- rstroposed
- rdtroposed
- rrtroposed
- r4troposed
- r3troposed
- rerroposed
- refroposed
- regroposed
- reyroposed
- re6roposed
- re5roposed
- reteoposed
- retdoposed
Etymology of RETROPOSED
The word "retroposed" is derived from the combination of two components: "retro" and "posed".
1. "Retro-" comes from the Latin prefix "retro", which means "backwards" or "behind". It is used to indicate a reversal or backward movement.
2. "Posed" is the past participle form of the verb "pose", which comes from Middle English and Old French, meaning "to place" or "to put in a particular way".
Therefore, the term "retroposed" combines the concept of something being moved or placed in a backward or reverse position. It is often used in genetics and molecular biology to describe a specific type of genetic rearrangement or duplication event.
Similar spelling words for RETROPOSED
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