QUINOLINONES Meaning and
Definition
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Quinolinones are a class of organic compounds that contain a quinoline ring fused with a ketone functional group. They are derived from the parent compound quinoline, which is a heterocyclic aromatic compound consisting of a benzene ring fused to a pyridine ring. Quinolinones are considered an important class of compounds due to their diverse range of biological and pharmacological activities.
In terms of their chemical structure, quinolinones are characterized by the presence of a carbonyl group (-C=O) attached to the quinoline ring. This ketone functionality imparts unique chemical properties to the compound, allowing for interactions with various biochemical targets. Quinolinones display aromaticity within their quinoline ring, which contributes to their stability and reactivity.
These compounds have attracted considerable interest in medicinal chemistry due to their ability to interact with specific enzymes, receptors, and proteins in the human body. They have been utilized as potential drug candidates for a wide array of therapeutic areas, including antiviral, antibacterial, anticancer, and antimalarial activities. Additionally, quinolinones have demonstrated properties such as antioxidant, anti-inflammatory, and analgesic effects.
The versatility of quinolinones has led to the exploration of different synthetic methods for their preparation, allowing for the synthesis of structurally diverse analogs. The development of new quinolinone derivatives continues to be an active area of research, aiming to design compounds with improved potency, selectivity, and pharmacokinetic properties for the treatment of various diseases.
Common Misspellings for QUINOLINONES
- 1uinolinones
- 2uinolinones
- wuinolinones
- auinolinones
- qyinolinones
- qhinolinones
- qjinolinones
- qiinolinones
- q8inolinones
- q7inolinones
- quunolinones
- qujnolinones
- quknolinones
- quonolinones
- qu9nolinones
- qu8nolinones
- quibolinones
- quimolinones
- quijolinones
- quiholinones
Etymology of QUINOLINONES
The word "Quinolinones" is derived from the compound's structure and composition. It combines two components:
1. "Quinoline": The term "quinoline" originates from the Latin word "quina" meaning "cinchona bark" and the Greek word "oleum" meaning "oil". Quinoline was initially isolated from cinchona bark and later recognized as an aromatic heterocyclic compound with a bicyclic structure containing a pyridine ring fused to a benzene ring.
2. "One": The suffix "-one" is derived from the Greek word "onos" meaning "being" or "existing". In chemical nomenclature, "-one" is used to indicate a ketone functional group (-C=O) attached to a carbon chain.
