How Do You Spell PROXIMAL RENAL TUBULAR DYSFUNCTION?

Pronunciation: [pɹˈɒksɪmə͡l ɹˈiːnə͡l tjˈuːbjʊlə dɪsfˈʌŋkʃən] (IPA)

Proximal Renal Tubular Dysfunction refers to a condition where the proximal renal tubules, which are responsible for reabsorbing essential nutrients, ions, and water from urine, fails to function properly. The word "proximal" is pronounced as /ˈprɒksɪməl/ with the first syllable having a short "o" sound /ɒ/ and the stress on the second syllable. "Renal" is pronounced as /ˈriːnəl/ with the stress on the first syllable and a long "e" sound /iː/. "Tubular" is pronounced as /ˈtjuːbjʊlər/ with the stress on the first syllable and a short "u" sound /ʊ/. Finally, "dysfunction" is pronounced as /dɪsˈfʌŋ

PROXIMAL RENAL TUBULAR DYSFUNCTION Meaning and Definition

  1. Proximal Renal Tubular Dysfunction refers to a condition characterized by impaired functioning of the proximal renal tubules. The proximal renal tubules are tiny tubes in the kidney responsible for the reabsorption of various essential substances, including glucose, amino acids, electrolytes, and other small molecules, from the urine back into the bloodstream. This process helps in maintaining the balance of electrolytes and other vital components in the body.

    In the case of proximal renal tubular dysfunction, there is a disruption in the proper reabsorption of these substances. This dysfunction can result from various underlying factors, including genetic abnormalities, certain medications, systemic diseases like Fanconi syndrome or Wilson's disease, and tubulointerstitial diseases.

    Common symptoms of proximal renal tubular dysfunction include excessive urination (polyuria), excessive thirst (polydipsia), dehydration, electrolyte imbalances, growth retardation or failure to thrive in children, bone disorders, and muscle weakness. Laboratory tests may reveal abnormally high levels of glucose, amino acids, electrolytes, and phosphate in the urine.

    Treatment for proximal renal tubular dysfunction primarily involves addressing the underlying cause, such as discontinuing medication or managing the associated systemic disease. Additionally, symptomatic treatment with medications may be necessary to control electrolyte imbalances or to enhance the reabsorption of specific substances in the renal tubules.

    Regular monitoring of kidney function and electrolyte levels is essential to assess the response to treatment and prevent complications associated with proximal renal tubular dysfunction.

Common Misspellings for PROXIMAL RENAL TUBULAR DYSFUNCTION

  • oroximal renal tubular dysfunction
  • lroximal renal tubular dysfunction
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  • prozimal renal tubular dysfunction
  • procimal renal tubular dysfunction
  • prodimal renal tubular dysfunction
  • prosimal renal tubular dysfunction

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