How Do You Spell PROXIMAL RENAL TUBULAR ACIDOSIS?

Pronunciation: [pɹˈɒksɪmə͡l ɹˈiːnə͡l tjˈuːbjʊləɹ ɐsɪdˈə͡ʊsɪs] (IPA)

The term "Proximal Renal Tubular Acidosis" refers to a condition where the kidneys are unable to properly regulate the acidity of the blood due to dysfunction in the proximal renal tubules. The word is spelled using the International Phonetic Alphabet (IPA) symbols for each sound in the word. This includes the "prɑksɪməl" (proximal) which is pronounced with a short "a" sound, and "rɛnəl" (renal) which is pronounced with a schwa sound. Additionally, "tubular" is pronounced as "tjubjʊlər" and "acidosis" as "əsɪdoʊsɪs."

PROXIMAL RENAL TUBULAR ACIDOSIS Meaning and Definition

  1. Proximal renal tubular acidosis (pRTA) is a medical condition characterized by the inability of the kidneys to properly reabsorb bicarbonate, resulting in a buildup of acid in the blood. The term "proximal" refers to the fact that the tubules affected are those located in the proximal (closest to the glomerulus) portion of the kidney.

    In a healthy individual, the proximal renal tubules play a crucial role in the reabsorption of filtered bicarbonate ions, which helps maintain the acid-base balance in the body. However, in individuals with pRTA, there is a defect in these tubules that impairs their ability to reabsorb bicarbonate. As a result, excess bicarbonate is lost in the urine, leading to a condition called metabolic acidosis.

    The main symptoms of pRTA include increased urine pH (alkaline urine), excessive thirst, frequent urination, difficulty in growth (in children), weakness, fatigue, and bone problems. Some individuals may also experience kidney stone formation or electrolyte imbalances, such as low blood potassium levels.

    The causes of pRTA can be acquired or inherited. Acquired causes include conditions like autoimmune diseases, certain medications, and toxic substances exposure. Inherited causes are often associated with genetic defects that affect the transporters responsible for bicarbonate reabsorption in the tubules.

    Treatment for pRTA primarily focuses on correcting the acid-base imbalance, maintaining adequate hydration, and addressing any electrolyte abnormalities. Medications such as alkali supplements or bicarbonate may be prescribed to help restore and maintain proper bicarbonate levels. Regular monitoring of kidney function, acid-base status, and electrolyte levels is crucial in managing this condition.

Common Misspellings for PROXIMAL RENAL TUBULAR ACIDOSIS

  • oroximal renal tubular acidosis
  • lroximal renal tubular acidosis
  • -roximal renal tubular acidosis
  • 0roximal renal tubular acidosis
  • peoximal renal tubular acidosis
  • pdoximal renal tubular acidosis
  • pfoximal renal tubular acidosis
  • ptoximal renal tubular acidosis
  • p5oximal renal tubular acidosis
  • p4oximal renal tubular acidosis
  • priximal renal tubular acidosis
  • prkximal renal tubular acidosis
  • prlximal renal tubular acidosis
  • prpximal renal tubular acidosis
  • pr0ximal renal tubular acidosis
  • pr9ximal renal tubular acidosis
  • prozimal renal tubular acidosis
  • procimal renal tubular acidosis
  • prodimal renal tubular acidosis
  • prosimal renal tubular acidosis

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