PRIMARY HYPEROXALURIA Meaning and
Definition
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Primary hyperoxaluria is a rare genetic disorder characterized by the excessive production and accumulation of oxalate in the body, leading to the formation and deposition of calcium oxalate crystals in various organs, primarily the kidneys. This condition is caused by a specific genetic mutation that affects the enzymes responsible for the breakdown of oxalate in the liver, resulting in its overproduction.
The excess oxalate cannot be properly eliminated from the body and instead accumulates and crystallizes in the kidneys, urinary tract, and other organs. The build-up of calcium oxalate crystals can cause various complications, including kidney stones, which can lead to severe pain, blood in the urine, and recurrent urinary tract infections. Over time, the crystals can also damage the kidneys, leading to chronic kidney disease and eventually, end-stage renal failure.
Primary hyperoxaluria is typically diagnosed in childhood but sometimes manifests in adulthood. Symptoms may include recurrent kidney stones, frequent urinary tract infections, abdominal pain, and blood in the urine. Due to its genetic nature, primary hyperoxaluria is a lifelong condition, and management often involves a combination of medical interventions such as dietary restrictions, hydration, and the use of medications to reduce oxalate production or promote its elimination. In severe cases, where kidney damage is extensive, a kidney transplant may be considered.
Common Misspellings for PRIMARY HYPEROXALURIA
- orimary hyperoxaluria
- lrimary hyperoxaluria
- -rimary hyperoxaluria
- 0rimary hyperoxaluria
- peimary hyperoxaluria
- pdimary hyperoxaluria
- pfimary hyperoxaluria
- ptimary hyperoxaluria
- p5imary hyperoxaluria
- p4imary hyperoxaluria
- prumary hyperoxaluria
- prjmary hyperoxaluria
- prkmary hyperoxaluria
- promary hyperoxaluria
- pr9mary hyperoxaluria
- pr8mary hyperoxaluria
- prinary hyperoxaluria
- prikary hyperoxaluria
- prijary hyperoxaluria
- primzry hyperoxaluria
Etymology of PRIMARY HYPEROXALURIA
The word "primary" in the term "Primary Hyperoxaluria" refers to the fact that this condition is the main or primary cause of excessive production of oxalate in the body.
"Hyperoxaluria" is derived from the Greek roots "hyper-" meaning excessive or over, and "oxalos" meaning oxalate or a type of salt. The suffix "-uria" refers to the presence of a substance in the urine. So, "hyperoxaluria" means an excessive amount of oxalate present in the urine.
Therefore, "Primary Hyperoxaluria" is a medical condition characterized by a genetic defect that causes excessive production of oxalate, leading to the accumulation of oxalate in various organs of the body, including the kidneys.
