PRIMARY HYPERALGESIA Meaning and
Definition
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Primary hyperalgesia is a term used in the field of medicine to describe a heightened sensitivity to pain that occurs at the site of tissue injury or inflammation. It refers to the phenomenon where there is an increased painful response to normally painful stimuli in the affected area. This increased sensitivity is a result of changes in the peripheral nerves that innervate the damaged tissue.
The process of primary hyperalgesia involves a complex interaction between various molecules and receptors in the body. Following tissue injury or inflammation, nociceptive nerve fibers located in the affected area become sensitized. This sensitization leads to an amplified response to painful stimuli, resulting in increased pain perception.
The symptoms of primary hyperalgesia can vary and may include increased pain intensity, enhanced response to mechanical stimulation, heightened sensitivity to thermal stimuli, and increased sensitivity to chemical mediators of inflammation.
Primary hyperalgesia is considered a protective mechanism as it signals the body to take precautions and prevent further damage to the injured tissue. However, in certain conditions, such as chronic pain syndromes, primary hyperalgesia can persist or become excessive, leading to ongoing pain and discomfort.
Understanding the underlying mechanisms of primary hyperalgesia is important for developing effective treatments and interventions to manage pain associated with tissue injury or inflammation.
Common Misspellings for PRIMARY HYPERALGESIA
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Etymology of PRIMARY HYPERALGESIA
The word "hyperalgesia" is derived from two Greek roots: "hyper", meaning excessive or above normal, and "algos", meaning pain. "Hyperalgesia" itself refers to an increased sensitivity to painful stimuli.
The word "primary" in "primary hyperalgesia" indicates that the condition is localized to the area of injury or inflammation. It specifically refers to the initial response of increased pain sensitivity that occurs at the site of tissue damage or inflammation.
Therefore, combining "primary" and "hyperalgesia" together, "primary hyperalgesia" can be understood as the intensified pain sensitivity that originates directly at the site of injury or inflammation.
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