How Do You Spell POLYINOSINIC POLYCYTIDYLIC ACID?

Pronunciation: [pˌɒlɪˌɪnəsˈɪnɪk pˌɒlɪsˌɪtɪdˈɪlɪk ˈasɪd] (IPA)

The spelling of "Polyinosinic Polycytidylic Acid" can be quite daunting, but it is pronounced as /pɑliˌaɪnoʊˌsɪnɪk ˌpɑliˌsaɪtɪˈdɪlɪk ˈæsɪd/. This tongue-twisting name refers to a synthetic double-stranded RNA molecule, which is used as an immune system booster and an antiviral agent. While the name may be a challenge to spell, it is synonymous with cutting-edge research and treatment of challenging conditions such as cancer, HIV, and viral diseases. Understanding the pronunciation is key to recognizing the significance of this complex term.

POLYINOSINIC POLYCYTIDYLIC ACID Meaning and Definition

1. Polyinosinic polycytidylic acid (poly(I:C)) is a synthetic analogue of double-stranded RNA (dsRNA) that is commonly used in molecular biology and immunology research. It is composed of a mixture of inosine and cytidine nucleotides, which form a long chain of repeating units.

   Poly(I:C) serves as a potent immune stimulant due to its ability to mimic the presence of viral RNA in the body, triggering a robust immune response. When administered to cells, poly(I:C) is recognized by pattern recognition receptors such as Toll-like receptor 3 (TLR-3) and cytosolic helicases like Retinoic acid inducible gene-I (RIG-I) and Melanoma differentiation-associated protein 5 (MDA5). These receptors activate specific signaling pathways that lead to the production of pro-inflammatory cytokines and type I interferons, key molecules involved in antiviral defense and immune regulation.

   Due to its immunostimulatory properties, poly(I:C) is frequently used to study antiviral responses, as well as for the development and testing of vaccines and antiviral drugs. It can be used in both in vitro and in vivo experiments to understand various aspects of immune signaling, including gene expression, cell activation, and cytokine release. Furthermore, poly(I:C) can be modified or conjugated with other molecules to enhance its stability, delivery, or targeting specificity in research and therapeutic applications.

Common Misspellings for POLYINOSINIC POLYCYTIDYLIC ACID

• oolyinosinic polycytidylic acid
• lolyinosinic polycytidylic acid
• -olyinosinic polycytidylic acid
• 0olyinosinic polycytidylic acid
• pilyinosinic polycytidylic acid
• pklyinosinic polycytidylic acid
• pllyinosinic polycytidylic acid
• pplyinosinic polycytidylic acid
• p0lyinosinic polycytidylic acid
• p9lyinosinic polycytidylic acid
• pokyinosinic polycytidylic acid
• popyinosinic polycytidylic acid
• pooyinosinic polycytidylic acid
• poltinosinic polycytidylic acid
• polginosinic polycytidylic acid
• polhinosinic polycytidylic acid
• poluinosinic polycytidylic acid
• pol7inosinic polycytidylic acid
• pol6inosinic polycytidylic acid
• polyunosinic polycytidylic acid