How Do You Spell PLATELET GLYCOPROTEIN IV?

Pronunciation: [plˈe͡ɪtlət ɡlˈa͡ɪkəpɹˌə͡ʊtiːn ɹˌə͡ʊmən fˈɔː] (IPA)

Platelet Glycoprotein IV is a biological term used to describe one of the glycoproteins found on the surface of platelets. It is pronounced as /plāt-let glī-kō-prō-tēn fȯr/. The word "platelet" is pronounced as /plāt-let/, while "glycoprotein" is pronounced as /glī-kō-prō-tēn/. The phonetic transcription for the letter "V" is /fȯr/, which has a silent "r" sound. The correct spelling of this complex term is crucial in the scientific world, where accuracy and attention to detail are highly valued.

PLATELET GLYCOPROTEIN IV Meaning and Definition

  1. Platelet Glycoprotein IV, also known as GPIV, is a cell surface glycoprotein that belongs to the immunoglobulin superfamily and is primarily expressed in platelets. It plays a crucial role in platelet adhesion and aggregation, which are essential processes in hemostasis and thrombosis.

    The GPIV protein consists of two extracellular immunoglobulin-like domains, a single transmembrane domain, and a short cytoplasmic tail. The extracellular domains facilitate interactions with other platelet surface proteins and ligands, such as collagen and fibrinogen.

    Platelet Glycoprotein IV is involved in the initial binding of platelets to collagen at sites of vascular injury. It acts as a receptor for collagen by binding to specific amino acid sequences within the extracellular matrix protein. This interaction promotes stable platelet adhesion and triggers signaling cascades that contribute to platelet activation and aggregation.

    Furthermore, GPIV is implicated in modulating platelet function during thrombus formation and stabilization. It has been found to regulate integrin activation and signaling events linked to platelet aggregation, contractility, and clot retraction.

    Research suggests that abnormalities in Platelet Glycoprotein IV expression or function can contribute to various platelet-related disorders, including bleeding disorders, thrombocytopenia, and thrombotic diseases. Therefore, studying the role of GPIV in platelet biology holds significant importance for understanding the underlying mechanisms of these conditions and can potentially lead to the development of targeted therapies.

Common Misspellings for PLATELET GLYCOPROTEIN IV

  • olatelet glycoprotein iv
  • llatelet glycoprotein iv
  • -latelet glycoprotein iv
  • 0latelet glycoprotein iv
  • pkatelet glycoprotein iv
  • ppatelet glycoprotein iv
  • poatelet glycoprotein iv
  • plztelet glycoprotein iv
  • plstelet glycoprotein iv
  • plwtelet glycoprotein iv
  • plqtelet glycoprotein iv
  • plarelet glycoprotein iv
  • plafelet glycoprotein iv
  • plagelet glycoprotein iv
  • playelet glycoprotein iv
  • pla6elet glycoprotein iv
  • pla5elet glycoprotein iv
  • platwlet glycoprotein iv
  • platslet glycoprotein iv
  • platdlet glycoprotein iv

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