How Do You Spell PLATELET GLYCOPROTEIN IIIB?

Pronunciation: [plˈe͡ɪtlət ɡlˈa͡ɪkəpɹˌə͡ʊtiːn ˈɪɪˌɪb] (IPA)

Platelet Glycoprotein IIIb is a complex term that requires attention to detail when it comes to spelling. The word "platelet" is pronounced as /ˈpleɪtlɪt/ with stress on the first syllable. "Glycoprotein" is pronounced as /ɡlaɪkəʊˈprəʊtiːn/ with stress on the third syllable. Lastly, "IIIb" uses Roman numerals and should be spelled as "three-bee". Paying attention to the phonetic transcription can help with the correct spelling of this important medical term.

PLATELET GLYCOPROTEIN IIIB Meaning and Definition

  1. Platelet Glycoprotein IIIb, also known as GPIIb, is a glycoprotein that is primarily expressed on the surface of platelets. It plays a crucial role in platelet aggregation, which is an essential step in the process of blood clot formation.

    GPIIb is classified as an integrin, a type of transmembrane receptor that can bind to ligands and mediate cell-cell and cell-matrix interactions. Specifically, GPIIb is a member of the integrin αIIbβ3 heterodimer. It consists of two subunits, αIIb (GPIIb) and β3 (GPIIIa), which are linked together to form a functional receptor complex on the platelet surface.

    The main function of GPIIb is to bind to fibrinogen and von Willebrand factor, which are critical for the initial steps of platelet aggregation and the formation of a stable blood clot. Upon platelet activation, GPIIb undergoes conformational changes that allow it to bind to fibrinogen, thereby activating the crosslinking of platelets and the formation of platelet aggregates.

    Abnormalities or deficiencies in GPIIb can lead to various bleeding disorders, such as Glanzmann thrombasthenia, where individuals are unable to form stable blood clots. On the other hand, excessive activation of GPIIb can contribute to pathological conditions like thrombosis, which is the formation of unnecessary blood clots within blood vessels.

    In summary, Platelet Glycoprotein IIIb (GPIIb) is a key receptor on platelets that mediates platelet aggregation and is essential for the formation of blood clots.

Common Misspellings for PLATELET GLYCOPROTEIN IIIB

  • olatelet glycoprotein iiib
  • llatelet glycoprotein iiib
  • -latelet glycoprotein iiib
  • 0latelet glycoprotein iiib
  • pkatelet glycoprotein iiib
  • ppatelet glycoprotein iiib
  • poatelet glycoprotein iiib
  • plztelet glycoprotein iiib
  • plstelet glycoprotein iiib
  • plwtelet glycoprotein iiib
  • plqtelet glycoprotein iiib
  • plarelet glycoprotein iiib
  • plafelet glycoprotein iiib
  • plagelet glycoprotein iiib
  • playelet glycoprotein iiib
  • pla6elet glycoprotein iiib
  • pla5elet glycoprotein iiib
  • platwlet glycoprotein iiib
  • platslet glycoprotein iiib
  • platdlet glycoprotein iiib

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